SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6geb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6geb DOTB
(Legionella
pneumophila) 		5 / 11 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.14A 1gtfU-6gebA:
undetectable
1gtfV-6gebA:
undetectable		 1gtfU-6gebA:
undetectable
1gtfV-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 THR A 251
GLY A 150
ALA A 245
THR A 290
ILE A 151
 None
 1.14A 1gtfL-6gebA:
undetectable
1gtfV-6gebA:
undetectable		 1gtfL-6gebA:
undetectable
1gtfV-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.15A 1gtnN-6gebA:
undetectable
1gtnO-6gebA:
undetectable		 1gtnN-6gebA:
undetectable
1gtnO-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 6geb DOTB
(Legionella
pneumophila) 		5 / 9 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.20A 1gtnR-6gebA:
undetectable
1gtnS-6gebA:
undetectable		 1gtnR-6gebA:
undetectable
1gtnS-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 6geb DOTB
(Legionella
pneumophila) 		4 / 7 GLY A 358
ASP A 304
VAL A 300
SER A 361
 None
 0.80A 2oa1B-6gebA:
undetectable		 2oa1B-6gebA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 6geb DOTB
(Legionella
pneumophila) 		5 / 12 LEU A  65
ASN A  62
LEU A  60
MET A  21
THR A  78
 None
 1.44A 2q7iA-6gebA:
undetectable		 2q7iA-6gebA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 6geb DOTB
(Legionella
pneumophila) 		5 / 12 LEU A  65
ASN A  62
LEU A  60
MET A  21
THR A  78
 None
 1.43A 2q7kA-6gebA:
undetectable		 2q7kA-6gebA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 6geb DOTB
(Legionella
pneumophila) 		5 / 12 LEU A  65
ASN A  62
LEU A  60
MET A  21
THR A  78
 None
 1.46A 2q7lA-6gebA:
undetectable		 2q7lA-6gebA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 6geb DOTB
(Legionella
pneumophila) 		4 / 6 LEU A 293
ILE A 169
ARG A 311
ILE A 141
 None
 0.93A 2q8hA-6gebA:
undetectable		 2q8hA-6gebA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QM9_A_TDZA201_2
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 6geb DOTB
(Legionella
pneumophila) 		4 / 4 TYR A 256
MET A 232
PRO A 129
ILE A 145
 None
 1.44A 2qm9A-6gebA:
undetectable		 2qm9A-6gebA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 6geb DOTB
(Legionella
pneumophila) 		5 / 12 LEU A  65
ASN A  62
LEU A  60
MET A  21
THR A  78
 None
 1.40A 2yloA-6gebA:
undetectable		 2yloA-6gebA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 6geb DOTB
(Legionella
pneumophila) 		4 / 4 PRO A 147
TYR A 256
GLY A 150
THR A 290
 None
 0.97A 3ib0A-6gebA:
undetectable		 3ib0A-6gebA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 6geb DOTB
(Legionella
pneumophila) 		5 / 12 LEU A  65
ASN A  62
LEU A  60
MET A  21
THR A  78
 None
 1.42A 3zqtA-6gebA:
undetectable		 3zqtA-6gebA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_A_ADNA401_1
(APH(2'')-ID)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 ALA A  28
ILE A  36
ILE A 120
LEU A  68
ILE A  38
 None
 1.26A 4dtaA-6gebA:
undetectable		 4dtaA-6gebA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 6geb DOTB
(Legionella
pneumophila) 		5 / 12 ILE A 174
TYR A 256
VAL A 152
LEU A 137
LEU A 132
 None
 1.34A 4qztA-6gebA:
1.3		 4qztA-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 6geb DOTB
(Legionella
pneumophila) 		3 / 3 THR A  40
ASN A  62
SER A  61
 None
 0.70A 4tvtA-6gebA:
undetectable		 4tvtA-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.14A 5eeuQ-6gebA:
undetectable
5eeuR-6gebA:
undetectable		 5eeuQ-6gebA:
undetectable
5eeuR-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eeuS-6gebA:
undetectable
5eeuT-6gebA:
undetectable		 5eeuS-6gebA:
undetectable
5eeuT-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eeuT-6gebA:
undetectable
5eeuU-6gebA:
undetectable		 5eeuT-6gebA:
undetectable
5eeuU-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eevO-6gebA:
undetectable
5eevP-6gebA:
undetectable		 5eevO-6gebA:
undetectable
5eevP-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eevQ-6gebA:
undetectable
5eevR-6gebA:
undetectable		 5eevQ-6gebA:
undetectable
5eevR-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eevS-6gebA:
undetectable
5eevT-6gebA:
undetectable		 5eevS-6gebA:
undetectable
5eevT-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eevT-6gebA:
undetectable
5eevU-6gebA:
undetectable		 5eevT-6gebA:
undetectable
5eevU-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eewO-6gebA:
undetectable
5eewP-6gebA:
undetectable		 5eewO-6gebA:
undetectable
5eewP-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eewQ-6gebA:
undetectable
5eewR-6gebA:
undetectable		 5eewQ-6gebA:
undetectable
5eewR-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eewS-6gebA:
undetectable
5eewT-6gebA:
undetectable		 5eewS-6gebA:
undetectable
5eewT-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eewT-6gebA:
undetectable
5eewU-6gebA:
undetectable		 5eewT-6gebA:
undetectable
5eewU-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eexO-6gebA:
undetectable
5eexP-6gebA:
undetectable		 5eexO-6gebA:
undetectable
5eexP-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 9 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eexQ-6gebA:
undetectable
5eexR-6gebA:
undetectable		 5eexQ-6gebA:
undetectable
5eexR-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.14A 5eexR-6gebA:
undetectable
5eexS-6gebA:
undetectable		 5eexR-6gebA:
undetectable
5eexS-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eexS-6gebA:
undetectable
5eexT-6gebA:
undetectable		 5eexS-6gebA:
undetectable
5eexT-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eexT-6gebA:
undetectable
5eexU-6gebA:
undetectable		 5eexT-6gebA:
undetectable
5eexU-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eeyO-6gebA:
undetectable
5eeyP-6gebA:
undetectable		 5eeyO-6gebA:
undetectable
5eeyP-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 9 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eeyQ-6gebA:
undetectable
5eeyR-6gebA:
undetectable		 5eeyQ-6gebA:
undetectable
5eeyR-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.14A 5eeyR-6gebA:
undetectable
5eeyS-6gebA:
undetectable		 5eeyR-6gebA:
undetectable
5eeyS-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.12A 5eeyS-6gebA:
undetectable
5eeyT-6gebA:
undetectable		 5eeyS-6gebA:
undetectable
5eeyT-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eeyT-6gebA:
undetectable
5eeyU-6gebA:
undetectable		 5eeyT-6gebA:
undetectable
5eeyU-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.15A 5eeyU-6gebA:
undetectable
5eeyV-6gebA:
undetectable		 5eeyU-6gebA:
undetectable
5eeyV-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eezO-6gebA:
undetectable
5eezP-6gebA:
undetectable		 5eezO-6gebA:
undetectable
5eezP-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 9 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eezQ-6gebA:
undetectable
5eezR-6gebA:
undetectable		 5eezQ-6gebA:
undetectable
5eezR-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eezS-6gebA:
undetectable
5eezT-6gebA:
undetectable		 5eezS-6gebA:
undetectable
5eezT-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5eezT-6gebA:
undetectable
5eezU-6gebA:
undetectable		 5eezT-6gebA:
undetectable
5eezU-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.15A 5eezU-6gebA:
undetectable
5eezV-6gebA:
undetectable		 5eezU-6gebA:
undetectable
5eezV-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.12A 5ef0O-6gebA:
undetectable
5ef0P-6gebA:
undetectable		 5ef0O-6gebA:
undetectable
5ef0P-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 9 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5ef0Q-6gebA:
undetectable
5ef0R-6gebA:
undetectable		 5ef0Q-6gebA:
undetectable
5ef0R-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.14A 5ef0R-6gebA:
undetectable
5ef0S-6gebA:
undetectable		 5ef0R-6gebA:
undetectable
5ef0S-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5ef0S-6gebA:
undetectable
5ef0T-6gebA:
undetectable		 5ef0S-6gebA:
undetectable
5ef0T-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.15A 5ef0U-6gebA:
undetectable
5ef0V-6gebA:
undetectable		 5ef0U-6gebA:
undetectable
5ef0V-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.12A 5ef1O-6gebA:
undetectable
5ef1P-6gebA:
undetectable		 5ef1O-6gebA:
undetectable
5ef1P-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 9 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5ef1Q-6gebA:
undetectable
5ef1R-6gebA:
undetectable		 5ef1Q-6gebA:
undetectable
5ef1R-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.14A 5ef1R-6gebA:
undetectable
5ef1S-6gebA:
undetectable		 5ef1R-6gebA:
undetectable
5ef1S-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5ef1S-6gebA:
undetectable
5ef1T-6gebA:
undetectable		 5ef1S-6gebA:
undetectable
5ef1T-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5ef1T-6gebA:
undetectable
5ef1U-6gebA:
undetectable		 5ef1T-6gebA:
undetectable
5ef1U-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.15A 5ef1U-6gebA:
undetectable
5ef1V-6gebA:
undetectable		 5ef1U-6gebA:
undetectable
5ef1V-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5ef2O-6gebA:
undetectable
5ef2P-6gebA:
undetectable		 5ef2O-6gebA:
undetectable
5ef2P-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 9 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5ef2Q-6gebA:
undetectable
5ef2R-6gebA:
undetectable		 5ef2Q-6gebA:
undetectable
5ef2R-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.14A 5ef2R-6gebA:
undetectable
5ef2S-6gebA:
undetectable		 5ef2R-6gebA:
undetectable
5ef2S-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5ef2S-6gebA:
undetectable
5ef2T-6gebA:
undetectable		 5ef2S-6gebA:
undetectable
5ef2T-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5ef2T-6gebA:
undetectable
5ef2U-6gebA:
undetectable		 5ef2T-6gebA:
undetectable
5ef2U-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.15A 5ef2U-6gebA:
undetectable
5ef2V-6gebA:
undetectable		 5ef2U-6gebA:
undetectable
5ef2V-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_P_TRPP101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5ef3O-6gebA:
undetectable
5ef3P-6gebA:
undetectable		 5ef3O-6gebA:
undetectable
5ef3P-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 9 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5ef3Q-6gebA:
undetectable
5ef3R-6gebA:
undetectable		 5ef3Q-6gebA:
undetectable
5ef3R-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.14A 5ef3R-6gebA:
undetectable
5ef3S-6gebA:
undetectable		 5ef3R-6gebA:
undetectable
5ef3S-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.13A 5ef3S-6gebA:
undetectable
5ef3T-6gebA:
undetectable		 5ef3S-6gebA:
undetectable
5ef3T-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6geb DOTB
(Legionella
pneumophila) 		5 / 10 GLY A 150
ALA A 245
THR A 290
ILE A 151
THR A 251
 None
 1.15A 5ef3U-6gebA:
undetectable
5ef3V-6gebA:
undetectable		 5ef3U-6gebA:
undetectable
5ef3V-6gebA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 6geb DOTB
(Legionella
pneumophila) 		4 / 7 ILE A  72
GLU A  92
HIS A  90
VAL A 105
 None
 1.08A 6j20A-6gebA:
undetectable		 6j20A-6gebA:
undetectable