SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gef'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.23A 1c9sJ-6gefA:
undetectable
1c9sK-6gefA:
undetectable
1c9sJ-6gefA:
undetectable
1c9sK-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.27A 1gtfC-6gefA:
undetectable
1gtfD-6gefA:
undetectable
1gtfC-6gefA:
undetectable
1gtfD-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.25A 1gtfG-6gefA:
undetectable
1gtfH-6gefA:
undetectable
1gtfG-6gefA:
undetectable
1gtfH-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.24A 1gtfH-6gefA:
undetectable
1gtfI-6gefA:
undetectable
1gtfH-6gefA:
undetectable
1gtfI-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.24A 1gtfI-6gefA:
undetectable
1gtfJ-6gefA:
undetectable
1gtfI-6gefA:
undetectable
1gtfJ-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.29A 1gtfT-6gefA:
undetectable
1gtfU-6gefA:
undetectable
1gtfT-6gefA:
undetectable
1gtfU-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 11 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.32A 1gtfU-6gefA:
undetectable
1gtfV-6gefA:
undetectable
1gtfU-6gefA:
undetectable
1gtfV-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.31A 1gtfL-6gefA:
undetectable
1gtfV-6gefA:
undetectable
1gtfL-6gefA:
undetectable
1gtfV-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.22A 1gtnG-6gefA:
undetectable
1gtnH-6gefA:
undetectable
1gtnG-6gefA:
undetectable
1gtnH-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.32A 1gtnN-6gefA:
undetectable
1gtnO-6gefA:
undetectable
1gtnN-6gefA:
undetectable
1gtnO-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
3 / 3 PHE A  21
TYR A  15
PRO A  18
PHE  A  21 ( 1.3A)
TYR  A  15 ( 1.3A)
PRO  A  18 ( 1.1A)
1.09A 1mcnA-6gefA:
undetectable
1mcnB-6gefA:
undetectable
1mcnP-6gefA:
undetectable
1mcnA-6gefA:
undetectable
1mcnB-6gefA:
undetectable
1mcnP-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKW_A_PNTA225_0
(TRANSCRIPTIONAL
REGULATOR QACR)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 12 GLU A  24
LYS A  28
TYR A  17
GLU A  22
ASN A  67
GLU  A  24 ( 0.6A)
LYS  A  28 ( 0.0A)
TYR  A  17 ( 1.3A)
GLU  A  22 ( 0.5A)
ASN  A  67 ( 0.6A)
1.31A 1rkwA-6gefA:
0.0
1rkwA-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.21A 1utdA-6gefA:
undetectable
1utdB-6gefA:
undetectable
1utdA-6gefA:
undetectable
1utdB-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.26A 1utdC-6gefA:
undetectable
1utdD-6gefA:
undetectable
1utdC-6gefA:
undetectable
1utdD-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.22A 1utdG-6gefA:
undetectable
1utdH-6gefA:
undetectable
1utdG-6gefA:
undetectable
1utdH-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.25A 1utdN-6gefA:
undetectable
1utdO-6gefA:
undetectable
1utdN-6gefA:
undetectable
1utdO-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.31A 1utdR-6gefA:
undetectable
1utdS-6gefA:
undetectable
1utdR-6gefA:
undetectable
1utdS-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 12 THR A 200
LEU A 199
ILE A 246
VAL A 270
PHE A 228
THR  A 200 ( 0.8A)
LEU  A 199 ( 0.5A)
ILE  A 246 ( 0.7A)
VAL  A 270 ( 0.6A)
PHE  A 228 ( 1.3A)
1.22A 1wsvA-6gefA:
undetectable
1wsvA-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 12 THR A 200
LEU A 199
ILE A 246
VAL A 270
PHE A 228
THR  A 200 ( 0.8A)
LEU  A 199 ( 0.5A)
ILE  A 246 ( 0.7A)
VAL  A 270 ( 0.6A)
PHE  A 228 ( 1.3A)
1.23A 1wsvB-6gefA:
undetectable
1wsvB-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
4 / 8 SER A  62
ARG A  64
LEU A  66
GLU A  70
SER  A  62 ( 0.0A)
ARG  A  64 ( 0.6A)
LEU  A  66 ( 0.5A)
GLU  A  70 ( 0.6A)
0.99A 2cdqA-6gefA:
1.3
2cdqA-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
4 / 7 SER A  62
ARG A  64
LEU A  66
GLU A  70
SER  A  62 ( 0.0A)
ARG  A  64 ( 0.6A)
LEU  A  66 ( 0.5A)
GLU  A  70 ( 0.6A)
1.10A 2cdqB-6gefA:
undetectable
2cdqB-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
4 / 5 VAL A 166
THR A 179
THR A 306
ARG A 307
VAL  A 166 ( 0.6A)
THR  A 179 ( 0.8A)
THR  A 306 ( 0.8A)
ARG  A 307 ( 0.6A)
1.11A 3bjwA-6gefA:
undetectable
3bjwA-6gefA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
4 / 5 VAL A 166
THR A 179
THR A 306
ARG A 307
VAL  A 166 ( 0.6A)
THR  A 179 ( 0.8A)
THR  A 306 ( 0.8A)
ARG  A 307 ( 0.6A)
1.11A 3bjwC-6gefA:
undetectable
3bjwC-6gefA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 ALA A  25
ILE A  50
LEU A  66
ILE A  74
TYR A  98
ALA  A  25 ( 0.0A)
ILE  A  50 ( 0.7A)
LEU  A  66 ( 0.5A)
ILE  A  74 ( 0.7A)
TYR  A  98 ( 1.3A)
1.27A 3jw3B-6gefA:
undetectable
3jw3B-6gefA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
4 / 5 ILE A 126
THR A 131
THR A 130
PHE A  68
ILE  A 126 ( 0.7A)
THR  A 131 ( 0.8A)
THR  A 130 ( 0.8A)
PHE  A  68 ( 1.3A)
0.89A 3snfA-6gefA:
undetectable
3snfA-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
4 / 5 VAL A 352
LEU A 329
ILE A 309
VAL A 303
VAL  A 352 ( 0.6A)
LEU  A 329 ( 0.6A)
ILE  A 309 ( 0.7A)
VAL  A 303 ( 0.6A)
0.98A 4a9kB-6gefA:
undetectable
4a9kB-6gefA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.26A 5eeuE-6gefA:
undetectable
5eeuF-6gefA:
undetectable
5eeuE-6gefA:
undetectable
5eeuF-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.27A 5eeuG-6gefA:
undetectable
5eeuH-6gefA:
undetectable
5eeuG-6gefA:
undetectable
5eeuH-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.23A 5eeuJ-6gefA:
undetectable
5eeuK-6gefA:
undetectable
5eeuJ-6gefA:
undetectable
5eeuK-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.33A 5eeuN-6gefA:
undetectable
5eeuO-6gefA:
undetectable
5eeuN-6gefA:
undetectable
5eeuO-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.30A 5eeuP-6gefA:
undetectable
5eeuQ-6gefA:
undetectable
5eeuP-6gefA:
undetectable
5eeuQ-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.28A 5eeuR-6gefA:
undetectable
5eeuS-6gefA:
undetectable
5eeuR-6gefA:
undetectable
5eeuS-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.30A 5eeuS-6gefA:
undetectable
5eeuT-6gefA:
undetectable
5eeuS-6gefA:
undetectable
5eeuT-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.28A 5eeuT-6gefA:
undetectable
5eeuU-6gefA:
undetectable
5eeuT-6gefA:
undetectable
5eeuU-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.31A 5eeuU-6gefA:
undetectable
5eeuV-6gefA:
undetectable
5eeuU-6gefA:
undetectable
5eeuV-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.26A 5eevE-6gefA:
undetectable
5eevF-6gefA:
undetectable
5eevE-6gefA:
undetectable
5eevF-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.27A 5eevG-6gefA:
undetectable
5eevH-6gefA:
undetectable
5eevG-6gefA:
undetectable
5eevH-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.23A 5eevJ-6gefA:
undetectable
5eevK-6gefA:
undetectable
5eevJ-6gefA:
undetectable
5eevK-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.33A 5eevN-6gefA:
undetectable
5eevO-6gefA:
undetectable
5eevN-6gefA:
undetectable
5eevO-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.30A 5eevP-6gefA:
undetectable
5eevQ-6gefA:
undetectable
5eevP-6gefA:
undetectable
5eevQ-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.29A 5eevR-6gefA:
undetectable
5eevS-6gefA:
undetectable
5eevR-6gefA:
undetectable
5eevS-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.30A 5eevS-6gefA:
undetectable
5eevT-6gefA:
undetectable
5eevS-6gefA:
undetectable
5eevT-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.28A 5eevT-6gefA:
undetectable
5eevU-6gefA:
undetectable
5eevT-6gefA:
undetectable
5eevU-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.32A 5eevU-6gefA:
undetectable
5eevV-6gefA:
undetectable
5eevU-6gefA:
undetectable
5eevV-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.27A 5eewE-6gefA:
undetectable
5eewF-6gefA:
undetectable
5eewE-6gefA:
undetectable
5eewF-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.27A 5eewG-6gefA:
undetectable
5eewH-6gefA:
undetectable
5eewG-6gefA:
undetectable
5eewH-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.23A 5eewJ-6gefA:
undetectable
5eewK-6gefA:
undetectable
5eewJ-6gefA:
undetectable
5eewK-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.33A 5eewN-6gefA:
undetectable
5eewO-6gefA:
undetectable
5eewN-6gefA:
undetectable
5eewO-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.30A 5eewP-6gefA:
undetectable
5eewQ-6gefA:
undetectable
5eewP-6gefA:
undetectable
5eewQ-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.29A 5eewR-6gefA:
undetectable
5eewS-6gefA:
undetectable
5eewR-6gefA:
undetectable
5eewS-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.30A 5eewS-6gefA:
undetectable
5eewT-6gefA:
undetectable
5eewS-6gefA:
undetectable
5eewT-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.28A 5eewT-6gefA:
undetectable
5eewU-6gefA:
undetectable
5eewT-6gefA:
undetectable
5eewU-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.32A 5eewU-6gefA:
undetectable
5eewV-6gefA:
undetectable
5eewU-6gefA:
undetectable
5eewV-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.26A 5eexE-6gefA:
undetectable
5eexF-6gefA:
undetectable
5eexE-6gefA:
undetectable
5eexF-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.27A 5eexG-6gefA:
undetectable
5eexH-6gefA:
undetectable
5eexG-6gefA:
undetectable
5eexH-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 11 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.24A 5eexI-6gefA:
undetectable
5eexJ-6gefA:
undetectable
5eexI-6gefA:
undetectable
5eexJ-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.23A 5eexJ-6gefA:
undetectable
5eexK-6gefA:
undetectable
5eexJ-6gefA:
undetectable
5eexK-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.33A 5eexN-6gefA:
undetectable
5eexO-6gefA:
undetectable
5eexN-6gefA:
undetectable
5eexO-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.30A 5eexP-6gefA:
undetectable
5eexQ-6gefA:
undetectable
5eexP-6gefA:
undetectable
5eexQ-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.31A 5eexQ-6gefA:
undetectable
5eexR-6gefA:
undetectable
5eexQ-6gefA:
undetectable
5eexR-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.29A 5eexR-6gefA:
undetectable
5eexS-6gefA:
undetectable
5eexR-6gefA:
undetectable
5eexS-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.30A 5eexS-6gefA:
undetectable
5eexT-6gefA:
undetectable
5eexS-6gefA:
undetectable
5eexT-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.28A 5eexT-6gefA:
undetectable
5eexU-6gefA:
undetectable
5eexT-6gefA:
undetectable
5eexU-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.32A 5eexU-6gefA:
undetectable
5eexV-6gefA:
undetectable
5eexU-6gefA:
undetectable
5eexV-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.27A 5eeyE-6gefA:
undetectable
5eeyF-6gefA:
undetectable
5eeyE-6gefA:
undetectable
5eeyF-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.27A 5eeyG-6gefA:
undetectable
5eeyH-6gefA:
undetectable
5eeyG-6gefA:
undetectable
5eeyH-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 11 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.24A 5eeyI-6gefA:
undetectable
5eeyJ-6gefA:
undetectable
5eeyI-6gefA:
undetectable
5eeyJ-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.23A 5eeyJ-6gefA:
undetectable
5eeyK-6gefA:
undetectable
5eeyJ-6gefA:
undetectable
5eeyK-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.33A 5eeyN-6gefA:
undetectable
5eeyO-6gefA:
undetectable
5eeyN-6gefA:
undetectable
5eeyO-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.30A 5eeyP-6gefA:
undetectable
5eeyQ-6gefA:
undetectable
5eeyP-6gefA:
undetectable
5eeyQ-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.31A 5eeyQ-6gefA:
undetectable
5eeyR-6gefA:
undetectable
5eeyQ-6gefA:
undetectable
5eeyR-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.29A 5eeyR-6gefA:
undetectable
5eeyS-6gefA:
undetectable
5eeyR-6gefA:
undetectable
5eeyS-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.30A 5eeyS-6gefA:
undetectable
5eeyT-6gefA:
undetectable
5eeyS-6gefA:
undetectable
5eeyT-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.28A 5eeyT-6gefA:
undetectable
5eeyU-6gefA:
undetectable
5eeyT-6gefA:
undetectable
5eeyU-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.32A 5eeyU-6gefA:
undetectable
5eeyV-6gefA:
undetectable
5eeyU-6gefA:
undetectable
5eeyV-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.26A 5eezE-6gefA:
undetectable
5eezF-6gefA:
undetectable
5eezE-6gefA:
undetectable
5eezF-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.27A 5eezG-6gefA:
undetectable
5eezH-6gefA:
undetectable
5eezG-6gefA:
undetectable
5eezH-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 11 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.24A 5eezI-6gefA:
undetectable
5eezJ-6gefA:
undetectable
5eezI-6gefA:
undetectable
5eezJ-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.23A 5eezJ-6gefA:
undetectable
5eezK-6gefA:
undetectable
5eezJ-6gefA:
undetectable
5eezK-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.33A 5eezN-6gefA:
undetectable
5eezO-6gefA:
undetectable
5eezN-6gefA:
undetectable
5eezO-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.30A 5eezP-6gefA:
undetectable
5eezQ-6gefA:
undetectable
5eezP-6gefA:
undetectable
5eezQ-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.31A 5eezQ-6gefA:
undetectable
5eezR-6gefA:
undetectable
5eezQ-6gefA:
undetectable
5eezR-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.29A 5eezR-6gefA:
undetectable
5eezS-6gefA:
undetectable
5eezR-6gefA:
undetectable
5eezS-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
ALA A 260
THR A 305
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
ALA  A 260 ( 0.0A)
THR  A 305 ( 0.8A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.12A 5eezS-6gefA:
undetectable
5eezT-6gefA:
undetectable
5eezS-6gefA:
undetectable
5eezT-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.31A 5eezS-6gefA:
undetectable
5eezT-6gefA:
undetectable
5eezS-6gefA:
undetectable
5eezT-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.28A 5eezT-6gefA:
undetectable
5eezU-6gefA:
undetectable
5eezT-6gefA:
undetectable
5eezU-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.32A 5eezU-6gefA:
undetectable
5eezV-6gefA:
undetectable
5eezU-6gefA:
undetectable
5eezV-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.27A 5ef0E-6gefA:
undetectable
5ef0F-6gefA:
undetectable
5ef0E-6gefA:
undetectable
5ef0F-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.27A 5ef0G-6gefA:
undetectable
5ef0H-6gefA:
undetectable
5ef0G-6gefA:
undetectable
5ef0H-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 11 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.24A 5ef0I-6gefA:
undetectable
5ef0J-6gefA:
undetectable
5ef0I-6gefA:
undetectable
5ef0J-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.23A 5ef0J-6gefA:
undetectable
5ef0K-6gefA:
undetectable
5ef0J-6gefA:
undetectable
5ef0K-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.33A 5ef0N-6gefA:
undetectable
5ef0O-6gefA:
undetectable
5ef0N-6gefA:
undetectable
5ef0O-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.30A 5ef0P-6gefA:
undetectable
5ef0Q-6gefA:
undetectable
5ef0P-6gefA:
undetectable
5ef0Q-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.31A 5ef0Q-6gefA:
undetectable
5ef0R-6gefA:
undetectable
5ef0Q-6gefA:
undetectable
5ef0R-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.29A 5ef0R-6gefA:
undetectable
5ef0S-6gefA:
undetectable
5ef0R-6gefA:
undetectable
5ef0S-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
ALA A 260
THR A 305
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
ALA  A 260 ( 0.0A)
THR  A 305 ( 0.8A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.12A 5ef0S-6gefA:
undetectable
5ef0T-6gefA:
undetectable
5ef0S-6gefA:
undetectable
5ef0T-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.31A 5ef0S-6gefA:
undetectable
5ef0T-6gefA:
undetectable
5ef0S-6gefA:
undetectable
5ef0T-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.32A 5ef0U-6gefA:
undetectable
5ef0V-6gefA:
undetectable
5ef0U-6gefA:
undetectable
5ef0V-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.26A 5ef1E-6gefA:
undetectable
5ef1F-6gefA:
undetectable
5ef1E-6gefA:
undetectable
5ef1F-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.27A 5ef1G-6gefA:
undetectable
5ef1H-6gefA:
undetectable
5ef1G-6gefA:
undetectable
5ef1H-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 11 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.24A 5ef1I-6gefA:
undetectable
5ef1J-6gefA:
undetectable
5ef1I-6gefA:
undetectable
5ef1J-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.23A 5ef1J-6gefA:
undetectable
5ef1K-6gefA:
undetectable
5ef1J-6gefA:
undetectable
5ef1K-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.33A 5ef1N-6gefA:
undetectable
5ef1O-6gefA:
undetectable
5ef1N-6gefA:
undetectable
5ef1O-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.30A 5ef1P-6gefA:
undetectable
5ef1Q-6gefA:
undetectable
5ef1P-6gefA:
undetectable
5ef1Q-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.31A 5ef1Q-6gefA:
undetectable
5ef1R-6gefA:
undetectable
5ef1Q-6gefA:
undetectable
5ef1R-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.29A 5ef1R-6gefA:
undetectable
5ef1S-6gefA:
undetectable
5ef1R-6gefA:
undetectable
5ef1S-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
ALA A 260
THR A 305
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
ALA  A 260 ( 0.0A)
THR  A 305 ( 0.8A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.12A 5ef1S-6gefA:
undetectable
5ef1T-6gefA:
undetectable
5ef1S-6gefA:
undetectable
5ef1T-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.31A 5ef1S-6gefA:
undetectable
5ef1T-6gefA:
undetectable
5ef1S-6gefA:
undetectable
5ef1T-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.28A 5ef1T-6gefA:
undetectable
5ef1U-6gefA:
undetectable
5ef1T-6gefA:
undetectable
5ef1U-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.32A 5ef1U-6gefA:
undetectable
5ef1V-6gefA:
undetectable
5ef1U-6gefA:
undetectable
5ef1V-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.26A 5ef2E-6gefA:
undetectable
5ef2F-6gefA:
undetectable
5ef2E-6gefA:
undetectable
5ef2F-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.27A 5ef2G-6gefA:
undetectable
5ef2H-6gefA:
undetectable
5ef2G-6gefA:
undetectable
5ef2H-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 11 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.24A 5ef2I-6gefA:
undetectable
5ef2J-6gefA:
undetectable
5ef2I-6gefA:
undetectable
5ef2J-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.23A 5ef2J-6gefA:
undetectable
5ef2K-6gefA:
undetectable
5ef2J-6gefA:
undetectable
5ef2K-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.33A 5ef2N-6gefA:
undetectable
5ef2O-6gefA:
undetectable
5ef2N-6gefA:
undetectable
5ef2O-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.30A 5ef2P-6gefA:
undetectable
5ef2Q-6gefA:
undetectable
5ef2P-6gefA:
undetectable
5ef2Q-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.31A 5ef2Q-6gefA:
undetectable
5ef2R-6gefA:
undetectable
5ef2Q-6gefA:
undetectable
5ef2R-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.29A 5ef2R-6gefA:
undetectable
5ef2S-6gefA:
undetectable
5ef2R-6gefA:
undetectable
5ef2S-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
ALA A 260
THR A 305
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
ALA  A 260 ( 0.0A)
THR  A 305 ( 0.8A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.12A 5ef2S-6gefA:
undetectable
5ef2T-6gefA:
undetectable
5ef2S-6gefA:
undetectable
5ef2T-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.31A 5ef2S-6gefA:
undetectable
5ef2T-6gefA:
undetectable
5ef2S-6gefA:
undetectable
5ef2T-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.29A 5ef2T-6gefA:
undetectable
5ef2U-6gefA:
undetectable
5ef2T-6gefA:
undetectable
5ef2U-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.32A 5ef2U-6gefA:
undetectable
5ef2V-6gefA:
undetectable
5ef2U-6gefA:
undetectable
5ef2V-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.26A 5ef3E-6gefA:
undetectable
5ef3F-6gefA:
undetectable
5ef3E-6gefA:
undetectable
5ef3F-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.27A 5ef3G-6gefA:
undetectable
5ef3H-6gefA:
undetectable
5ef3G-6gefA:
undetectable
5ef3H-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 11 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.24A 5ef3I-6gefA:
undetectable
5ef3J-6gefA:
undetectable
5ef3I-6gefA:
undetectable
5ef3J-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 THR A 266
GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR  A 266 ( 0.8A)
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
1.23A 5ef3J-6gefA:
undetectable
5ef3K-6gefA:
undetectable
5ef3J-6gefA:
undetectable
5ef3K-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.33A 5ef3N-6gefA:
undetectable
5ef3O-6gefA:
undetectable
5ef3N-6gefA:
undetectable
5ef3O-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.30A 5ef3P-6gefA:
undetectable
5ef3Q-6gefA:
undetectable
5ef3P-6gefA:
undetectable
5ef3Q-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 9 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.31A 5ef3Q-6gefA:
undetectable
5ef3R-6gefA:
undetectable
5ef3Q-6gefA:
undetectable
5ef3R-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.29A 5ef3R-6gefA:
undetectable
5ef3S-6gefA:
undetectable
5ef3R-6gefA:
undetectable
5ef3S-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
ALA A 260
THR A 305
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
ALA  A 260 ( 0.0A)
THR  A 305 ( 0.8A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.12A 5ef3S-6gefA:
undetectable
5ef3T-6gefA:
undetectable
5ef3S-6gefA:
undetectable
5ef3T-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.31A 5ef3S-6gefA:
undetectable
5ef3T-6gefA:
undetectable
5ef3S-6gefA:
undetectable
5ef3T-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 10 GLY A 164
HIS A 268
ALA A 260
ILE A 165
THR A 266
GLY  A 164 ( 0.0A)
HIS  A 268 ( 1.0A)
ALA  A 260 ( 0.0A)
ILE  A 165 ( 0.7A)
THR  A 266 ( 0.8A)
1.32A 5ef3U-6gefA:
undetectable
5ef3V-6gefA:
undetectable
5ef3U-6gefA:
undetectable
5ef3V-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
5 / 12 LEU A 251
VAL A 274
ALA A 311
ALA A 169
GLY A 170
LEU  A 251 ( 0.5A)
VAL  A 274 ( 0.6A)
ALA  A 311 ( 0.0A)
ALA  A 169 ( 0.0A)
GLY  A 170 ( 0.0A)
1.12A 5tzoB-6gefA:
undetectable
5tzoB-6gefA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
4 / 7 SER A 181
THR A 178
PRO A 140
ILE A 139
SER  A 181 ( 0.0A)
THR  A 178 ( 0.8A)
PRO  A 140 ( 1.1A)
ILE  A 139 ( 0.7A)
1.23A 5vkqA-6gefA:
undetectable
5vkqB-6gefA:
undetectable
5vkqA-6gefA:
undetectable
5vkqB-6gefA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
6gef TYPE IV SECRETION
SYSTEM PROTEIN DOTB

(Yersinia
pseudotuberculos
is)
4 / 7 SER A 181
THR A 178
PRO A 140
ILE A 139
SER  A 181 ( 0.0A)
THR  A 178 ( 0.8A)
PRO  A 140 ( 1.1A)
ILE  A 139 ( 0.7A)
1.22A 5vkqC-6gefA:
undetectable
5vkqD-6gefA:
undetectable
5vkqC-6gefA:
undetectable
5vkqD-6gefA:
undetectable