SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ggp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6ggp AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN
(Thermotoga
maritima) 		5 / 11 SER A  35
GLY A  33
VAL A  72
SER A  93
ILE A  88
 None
 1.22A 1pk9C-6ggpA:
undetectable		 1pk9C-6ggpA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 6ggp AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN
(Thermotoga
maritima) 		4 / 6 LEU A  57
TYR A 111
ILE A 224
ILE A  92
 None
 0.86A 2q8hA-6ggpA:
undetectable		 2q8hA-6ggpA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 6ggp AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN
(Thermotoga
maritima) 		5 / 12 LEU A 231
LEU A  57
ARG A 229
LEU A  30
VAL A  32
 None
 1.27A 2qd4A-6ggpA:
undetectable		 2qd4A-6ggpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 6ggp AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN
(Thermotoga
maritima) 		3 / 3 GLU A  60
LEU A  57
ASP A  56
 None
 0.47A 3ko0A-6ggpA:
undetectable		 3ko0A-6ggpA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 6ggp AMINO ACID ABC
TRANSPORTER,
PERIPLASMIC AMINO
ACID-BINDING PROTEIN
(Thermotoga
maritima) 		3 / 3 GLU A  60
LEU A  57
ASP A  56
 None
 0.42A 3ko0T-6ggpA:
undetectable		 3ko0T-6ggpA:
23.71