SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gh8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OIP_A_VIVA1278_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 6gh8 -
(-) 		5 / 12 LEU A 100
ILE A 122
LEU A  70
ILE A  68
ILE A  40
 None
 0.93A 1oipA-6gh8A:
undetectable		 1oipA-6gh8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 6gh8 -
(-) 		5 / 12 ILE A 141
ILE A  88
ILE A 122
VAL A  59
ILE A  90
 None
 1.34A 1r5lA-6gh8A:
undetectable		 1r5lA-6gh8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 6gh8 -
(-) 		4 / 6 GLN A 131
TYR A  49
PHE A 124
PRO A  43
 None
 1.27A 3tgvB-6gh8A:
undetectable		 3tgvB-6gh8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 6gh8 -
(-) 		4 / 6 GLN A 131
TYR A  49
PHE A 124
PRO A  43
 None
 1.23A 3tgvD-6gh8A:
undetectable		 3tgvD-6gh8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6gh8 -
(-) 		4 / 5 ARG A 138
VAL A  59
LEU A  32
SER A  34
 None
 1.34A 4e1gA-6gh8A:
undetectable		 4e1gA-6gh8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 6gh8 -
(-) 		4 / 7 VAL D 153
GLN D 188
TYR D 151
LEU D 102
 None
 0.98A 4hxyB-6gh8D:
undetectable		 4hxyB-6gh8D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 6gh8 -
(-) 		4 / 8 TRP A  57
ASP A  92
TYR A 121
LEU A 100
 None
 1.13A 5b1bA-6gh8A:
undetectable
5b1bC-6gh8A:
undetectable
5b1bP-6gh8A:
undetectable		 5b1bA-6gh8A:
undetectable
5b1bC-6gh8A:
undetectable
5b1bP-6gh8A:
undetectable