SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ghc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 6ghc -
(-) 		5 / 12 PHE A  86
VAL A  59
ILE A  47
SER A  92
LEU A  88
 None
 1.05A 1fm4A-6ghcA:
undetectable		 1fm4A-6ghcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 6ghc -
(-) 		4 / 6 ILE A 124
CYH A 101
LEU A  88
ILE A  48
 None
 0.87A 2q83B-6ghcA:
undetectable		 2q83B-6ghcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 6ghc -
(-) 		3 / 3 ARG A 120
GLY A 118
SER A  65
 None
 0.45A 2xctB-6ghcA:
2.8		 2xctB-6ghcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 6ghc -
(-) 		4 / 4 LYS A 168
SER A 171
LEU A 148
SER A 149
 None
 1.44A 3ik6H-6ghcA:
undetectable		 3ik6H-6ghcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 6ghc -
(-) 		4 / 5 LYS A 168
SER A 171
LEU A 148
SER A 149
 None
 1.40A 3iluH-6ghcA:
undetectable		 3iluH-6ghcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 6ghc -
(-) 		3 / 3 LEU A 125
ARG A 123
ARG A  78
 None
 0.85A 4yiaB-6ghcA:
undetectable		 4yiaB-6ghcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 6ghc -
(-) 		4 / 6 PHE A  86
LYS A  99
LEU A  98
ASN A  41
 None
 1.32A 4yv5B-6ghcA:
undetectable		 4yv5B-6ghcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_A_GBMA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 6ghc -
(-) 		5 / 11 LEU A 275
TYR A 269
ILE A 199
LEU A 255
LEU A 247
 None
 1.43A 4yvpA-6ghcA:
undetectable		 4yvpA-6ghcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 6ghc -
(-) 		4 / 8 ILE A  27
ARG A 123
TYR A  40
ASP A  21
 None
 0.91A 5vlmF-6ghcA:
undetectable		 5vlmF-6ghcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 6ghc -
(-) 		3 / 3 TYR A  46
ASP A  39
ASP A   5
 None
 0.84A 5x6yA-6ghcA:
undetectable		 5x6yA-6ghcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 6ghc -
(-) 		3 / 3 PRO A 232
SER A 234
SER A 235
 None
 0.39A 6bpyA-6ghcA:
undetectable		 6bpyA-6ghcA:
undetectable