SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gi2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 6gi2 FERRIC ENTEROBACTIN
ESTERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  67
ALA A  85
GLY A  87
LEU A 262
PHE A  22
 None
 1.39A 1brpA-6gi2A:
undetectable		 1brpA-6gi2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 6gi2 FERRIC ENTEROBACTIN
ESTERASE
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  27
LEU A 131
ARG A 170
VAL A  84
TRP A  56
 None
 1.23A 1hrkB-6gi2A:
undetectable		 1hrkB-6gi2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)		 6gi2 FERRIC ENTEROBACTIN
ESTERASE
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 150
GLN A  45
PRO A  48
 None
 0.98A 2qhfA-6gi2A:
undetectable		 2qhfA-6gi2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 6gi2 FERRIC ENTEROBACTIN
ESTERASE
(Pseudomonas
aeruginosa) 		5 / 8 LEU A  27
TYR A  88
TYR A  36
PHE A 128
LEU A 131
 None
 1.39A 3i45A-6gi2A:
2.4		 3i45A-6gi2A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_2
(POL POLYPROTEIN)		 6gi2 FERRIC ENTEROBACTIN
ESTERASE
(Pseudomonas
aeruginosa) 		5 / 9 ARG A 222
ILE A 191
GLY A 189
PRO A 116
LEU A 117
 8SW  A 302 ( 4.1A)
None
None
None
8SW  A 302 (-4.3A)
 1.16A 3u7sB-6gi2A:
undetectable		 3u7sB-6gi2A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)		 6gi2 FERRIC ENTEROBACTIN
ESTERASE
(Pseudomonas
aeruginosa) 		5 / 12 SER A  29
THR A 104
ALA A 125
ALA A 127
TYR A  88
 None
 1.35A 4u14A-6gi2A:
undetectable		 4u14A-6gi2A:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 6gi2 FERRIC ENTEROBACTIN
ESTERASE
(Pseudomonas
aeruginosa) 		5 / 12 SER A  29
THR A 104
ALA A 125
ALA A 127
TYR A  88
 None
 1.42A 4u15B-6gi2A:
undetectable		 4u15B-6gi2A:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 6gi2 FERRIC ENTEROBACTIN
ESTERASE
(Pseudomonas
aeruginosa) 		4 / 5 LEU A 129
ASP A 130
LEU A 162
THR A 169
 None
 1.11A 4wozF-6gi2A:
undetectable
4wozH-6gi2A:
undetectable		 4wozF-6gi2A:
undetectable
4wozH-6gi2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 6gi2 FERRIC ENTEROBACTIN
ESTERASE
(Pseudomonas
aeruginosa) 		6 / 12 GLY A 160
GLY A 155
THR A 261
ILE A 191
GLU A 194
LEU A 161
 None
 1.48A 5bw4A-6gi2A:
undetectable		 5bw4A-6gi2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 6gi2 FERRIC ENTEROBACTIN
ESTERASE
(Pseudomonas
aeruginosa) 		5 / 12 PHE A 174
LEU A 153
LEU A 162
ILE A  86
LEU A 146
 None
 1.05A 5h8tA-6gi2A:
undetectable		 5h8tA-6gi2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 6gi2 FERRIC ENTEROBACTIN
ESTERASE
(Pseudomonas
aeruginosa) 		5 / 12 PHE A 174
LEU A 153
LEU A 162
ILE A  86
LEU A 146
 None
 1.02A 5ljeA-6gi2A:
undetectable		 5ljeA-6gi2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 6gi2 FERRIC ENTEROBACTIN
ESTERASE
(Pseudomonas
aeruginosa) 		4 / 6 ARG A 176
ALA A 175
THR A 152
ALA A 274
 None
 1.18A 6ma6A-6gi2A:
undetectable		 6ma6A-6gi2A:
18.60