SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gkv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FK8_A_SAMA302_1 (METHOXY MYCOLIC ACID SYNTHASE 4)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	3 / 3	SER A 99 THR A 160 GLN A 165	SAH A 501 (-2.4A) SAH A 501 ( 4.8A) SAH A 501 (-2.7A)	0.38A	2fk8A-6gkvA: 26.1	2fk8A-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_B_SAMB303_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	ASP A 135 LEU A 136 GLY A 137 GLY A 139 LEU A 143	None None SAH A 501 (-3.5A) SAH A 501 (-3.1A) None	0.84A	2nxeB-6gkvA: 11.4	2nxeB-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_B_SAMB303_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	ASP A 135 LEU A 136 GLY A 137 GLY A 139 LEU A 205	None None SAH A 501 (-3.5A) SAH A 501 (-3.1A) SAH A 501 (-4.3A)	0.75A	2nxeB-6gkvA: 11.4	2nxeB-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_B_SAMB303_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	GLY A 98 LEU A 136 GLY A 137 GLY A 139 LEU A 205	SAH A 501 (-3.9A) None SAH A 501 (-3.5A) SAH A 501 (-3.1A) SAH A 501 (-4.3A)	0.87A	2nxeB-6gkvA: 11.4	2nxeB-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OXT_B_SAMB300_0 (NUCLEOSIDE-2'-O-METH YLTRANSFERASE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	GLY A 137 GLY A 139 GLY A 141 THR A 160 ILE A 188	SAH A 501 (-3.5A) SAH A 501 (-3.1A) None SAH A 501 ( 4.8A) SAH A 501 (-3.9A)	0.73A	2oxtB-6gkvA: 7.6	2oxtB-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3D9L_A_ACTA501_0 (CTD-PEPTIDE RNA-BINDING PROTEIN 16)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	4 / 5	PRO A 265 ILE A 263 TYR A 241 TYR A 243	None	1.35A	3d9lA-6gkvA: undetectable 3d9lY-6gkvA: undetectable	3d9lA-6gkvA: undetectable 3d9lY-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_A_CHDA150_0 (ILEAL BILE ACID-BINDING PROTEIN)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	TRP A 329 MET A 311 VAL A 323 LEU A 88 ILE A 90	None	1.37A	3elzA-6gkvA: undetectable	3elzA-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IHT_A_SAMA200_0 (S-ADENOSYL-L-METHION INE METHYL TRANSFERASE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	6 / 12	GLY A 137 GLY A 139 GLY A 141 ASP A 187 ILE A 188 LEU A 205	SAH A 501 (-3.5A) SAH A 501 (-3.1A) None SAH A 501 (-4.2A) SAH A 501 (-3.9A) SAH A 501 (-4.3A)	0.77A	3ihtA-6gkvA: 7.3	3ihtA-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_A_SAMA301_0 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	GLY A 137 SER A 162 ASP A 187 THR A 189 LEU A 205	SAH A 501 (-3.5A) None SAH A 501 (-4.2A) None SAH A 501 (-4.3A)	0.62A	3iv6A-6gkvA: 14.1	3iv6A-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IV6_A_SAMA301_0 (PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	SER A 162 ASP A 187 ILE A 188 THR A 189 LEU A 205	None SAH A 501 (-4.2A) SAH A 501 (-3.9A) None SAH A 501 (-4.3A)	0.75A	3iv6A-6gkvA: 14.1	3iv6A-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PFG_A_SAMA264_0 (N-METHYLTRANSFERASE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	TYR A 81 GLY A 139 SER A 162 ASP A 187 HIS A 208	SAH A 501 (-3.6A) SAH A 501 (-3.1A) None SAH A 501 (-4.2A) SAH A 501 ( 4.6A)	0.97A	3pfgA-6gkvA: 13.3	3pfgA-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F84_A_SAMA501_0 (GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERAS E)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	GLY A 137 GLY A 139 VAL A 159 THR A 160 GLN A 165	SAH A 501 (-3.5A) SAH A 501 (-3.1A) None SAH A 501 ( 4.8A) SAH A 501 (-2.7A)	0.51A	4f84A-6gkvA: 20.0	4f84A-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGZ_B_CQAB302_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	4 / 8	GLU A 170 GLU A 167 TYR A 168 GLY A 141	None	0.96A	4fgzA-6gkvA: 23.8 4fgzB-6gkvA: 23.8	4fgzA-6gkvA: undetectable 4fgzB-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IV0_B_SAMB302_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	GLY A 137 GLY A 139 ASP A 187 ILE A 188 HIS A 208	SAH A 501 (-3.5A) SAH A 501 (-3.1A) SAH A 501 (-4.2A) SAH A 501 (-3.9A) SAH A 501 ( 4.6A)	0.70A	4iv0B-6gkvA: 22.5	4iv0B-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IV0_B_SAMB302_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	TYR A 81 GLY A 137 GLY A 139 ASP A 187 HIS A 208	SAH A 501 (-3.6A) SAH A 501 (-3.5A) SAH A 501 (-3.1A) SAH A 501 (-4.2A) SAH A 501 ( 4.6A)	0.89A	4iv0B-6gkvA: 22.5	4iv0B-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_A_SAMA900_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	TYR A 81 GLY A 137 GLY A 139 ASP A 187 HIS A 208	SAH A 501 (-3.6A) SAH A 501 (-3.5A) SAH A 501 (-3.1A) SAH A 501 (-4.2A) SAH A 501 ( 4.6A)	0.74A	4krhA-6gkvA: 23.4	4krhA-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KRH_A_SAMA900_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	TYR A 81 GLY A 137 GLY A 139 SER A 162 ASP A 187	SAH A 501 (-3.6A) SAH A 501 (-3.5A) SAH A 501 (-3.1A) None SAH A 501 (-4.2A)	0.94A	4krhA-6gkvA: 23.4	4krhA-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L3G_F_ACTF401_0 (METHYLAMINE DEHYDROGENASE HEAVY CHAIN)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	3 / 3	ARG A 36 LEU A 33 GLU A 37	None	0.76A	4l3gF-6gkvA: undetectable	4l3gF-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N48_A_SAMA601_0 (CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-M ETHYLTRANSFERASE 1)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	GLY A 139 GLY A 141 THR A 160 ILE A 188 THR A 189	SAH A 501 (-3.1A) None SAH A 501 ( 4.8A) SAH A 501 (-3.9A) None	0.78A	4n48A-6gkvA: 7.4	4n48A-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N49_A_SAMA601_0 (CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-M ETHYLTRANSFERASE 1)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	GLY A 139 GLY A 141 THR A 160 ILE A 188 THR A 189	SAH A 501 (-3.1A) None SAH A 501 ( 4.8A) SAH A 501 (-3.9A) None	0.81A	4n49A-6gkvA: 7.1	4n49A-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PGF_A_ADNA502_1 (ADENOSYLHOMOCYSTEINA SE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	LEU A 80 LEU A 88 ASN A 92 GLY A 98 PHE A 257	None None None SAH A 501 (-3.9A) F2W A 502 (-4.5A)	1.11A	4pgfA-6gkvA: 3.2	4pgfA-6gkvA: 12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZZB_E_ACTE403_0 (PROTON-GATED ION CHANNEL)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	3 / 3	ARG A 176 TYR A 168 GLU A 172	None	0.67A	4zzbE-6gkvA: undetectable	4zzbE-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_D_SORD1341_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	4 / 6	CYH A 235 GLU A 347 GLY A 345 GLY A 287	None	1.01A	5a06D-6gkvA: 3.1	5a06D-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KOC_A_SAMA401_0 (PAVINE N-METHYLTRANSFERASE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	7 / 12	GLY A 139 ASN A 161 GLN A 165 ASP A 187 THR A 189 LEU A 205 HIS A 208	SAH A 501 (-3.1A) SAH A 501 (-3.6A) SAH A 501 (-2.7A) SAH A 501 (-4.2A) None SAH A 501 (-4.3A) SAH A 501 ( 4.6A)	0.66A	5kocA-6gkvA: 48.5	5kocA-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KOC_B_SAMB401_0 (PAVINE N-METHYLTRANSFERASE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	8 / 12	SER A 99 GLY A 137 GLY A 139 THR A 160 ASN A 161 GLN A 165 LEU A 205 HIS A 208	SAH A 501 (-2.4A) SAH A 501 (-3.5A) SAH A 501 (-3.1A) SAH A 501 ( 4.8A) SAH A 501 (-3.6A) SAH A 501 (-2.7A) SAH A 501 (-4.3A) SAH A 501 ( 4.6A)	0.63A	5kocB-6gkvA: 48.1	5kocB-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KPC_A_SAMA401_1 (PAVINE N-METHYLTRANSFERASE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	4 / 5	SER A 99 ASN A 161 GLN A 165 ASP A 187	SAH A 501 (-2.4A) SAH A 501 (-3.6A) SAH A 501 (-2.7A) SAH A 501 (-4.2A)	0.87A	5kpcA-6gkvA: 47.8	5kpcA-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KPC_B_SAMB401_0 (PAVINE N-METHYLTRANSFERASE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	9 / 12	LYS A 97 SER A 99 GLY A 137 GLY A 139 ASN A 161 SER A 162 GLN A 165 ASP A 187 THR A 189	SAH A 501 ( 4.5A) SAH A 501 (-2.4A) SAH A 501 (-3.5A) SAH A 501 (-3.1A) SAH A 501 (-3.6A) None SAH A 501 (-2.7A) SAH A 501 (-4.2A) None	0.81A	5kpcB-6gkvA: 45.8	5kpcB-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WY0_A_SAMA800_0 (SMALL RNA 2'-O-METHYLTRANSFERA SE)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	GLY A 137 GLY A 139 ILE A 203 LEU A 205 HIS A 208	SAH A 501 (-3.5A) SAH A 501 (-3.1A) SAH A 501 (-4.2A) SAH A 501 (-4.3A) SAH A 501 ( 4.6A)	0.51A	5wy0A-6gkvA: 11.1	5wy0A-6gkvA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A7J_A_TESA502_0 (CYTOCHROME P450)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	4 / 7	LEU A 88 LEU A 96 ALA A 142 THR A 160	None None SAH A 501 ( 4.7A) SAH A 501 ( 4.8A)	0.79A	6a7jA-6gkvA: undetectable	6a7jA-6gkvA: 23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HWD_B_BO2B201_0 (PROTEASOME SUBUNIT BETA TYPE-1 PROTEASOME SUBUNIT BETA TYPE-2)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	THR A 144 ALA A 148 GLY A 137 ALA A 158 THR A 160	None None SAH A 501 (-3.5A) None SAH A 501 ( 4.8A)	1.24A	6hwdV-6gkvA: undetectable 6hwdb-6gkvA: undetectable	6hwdV-6gkvA: 23.53 6hwdb-6gkvA: 20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HWD_N_BO2N201_0 (PROTEASOME SUBUNIT BETA TYPE-1 PROTEASOME SUBUNIT BETA TYPE-2)	6gkv	COCLAURINE N-METHYLTRANSFERASE (Coptis japonica)	5 / 12	THR A 144 ALA A 148 GLY A 137 ALA A 158 THR A 160	None None SAH A 501 (-3.5A) None SAH A 501 ( 4.8A)	1.24A	6hwdH-6gkvA: undetectable 6hwdN-6gkvA: undetectable	6hwdH-6gkvA: 23.53 6hwdN-6gkvA: 20.48

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2FK8_A_SAMA302_1","METHOXY MYCOLIC ACID SYNTHASE 4","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",3,"SER A  99;THR A 160;GLN A 165","SAH A 501 (-2.4A);SAH A 501 ( 4.8A);SAH A 501 (-2.7A)","0.38A","2fk8A-6gkvA:26.1","2fk8A-6gkvA:undetectable"],["2NXE_B_SAMB303_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"ASP A 135;LEU A 136;GLY A 137;GLY A 139;LEU A 143","None;None;SAH A 501 (-3.5A);SAH A 501 (-3.1A);None","0.84A","2nxeB-6gkvA:11.4","2nxeB-6gkvA:undetectable"],["2NXE_B_SAMB303_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"ASP A 135;LEU A 136;GLY A 137;GLY A 139;LEU A 205","None;None;SAH A 501 (-3.5A);SAH A 501 (-3.1A);SAH A 501 (-4.3A)","0.75A","2nxeB-6gkvA:11.4","2nxeB-6gkvA:undetectable"],["2NXE_B_SAMB303_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"GLY A  98;LEU A 136;GLY A 137;GLY A 139;LEU A 205","SAH A 501 (-3.9A);None;SAH A 501 (-3.5A);SAH A 501 (-3.1A);SAH A 501 (-4.3A)","0.87A","2nxeB-6gkvA:11.4","2nxeB-6gkvA:undetectable"],["2OXT_B_SAMB300_0","NUCLEOSIDE-2'-O-METHYLTRANSFERASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"GLY A 137;GLY A 139;GLY A 141;THR A 160;ILE A 188","SAH A 501 (-3.5A);SAH A 501 (-3.1A);None;SAH A 501 ( 4.8A);SAH A 501 (-3.9A)","0.73A","2oxtB-6gkvA:7.6","2oxtB-6gkvA:undetectable"],["3D9L_A_ACTA501_0","CTD-PEPTIDE;RNA-BINDING PROTEIN 16","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",4,"PRO A 265;ILE A 263;TYR A 241;TYR A 243","None","1.35A","3d9lA-6gkvA:undetectable;3d9lY-6gkvA:undetectable","3d9lA-6gkvA:undetectable;3d9lY-6gkvA:undetectable"],["3ELZ_A_CHDA150_0","ILEAL BILE ACID-BINDING PROTEIN","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"TRP A 329;MET A 311;VAL A 323;LEU A  88;ILE A  90","None","1.37A","3elzA-6gkvA:undetectable","3elzA-6gkvA:undetectable"],["3IHT_A_SAMA200_0","S-ADENOSYL-L-METHIONINE METHYL TRANSFERASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",6,"GLY A 137;GLY A 139;GLY A 141;ASP A 187;ILE A 188;LEU A 205","SAH A 501 (-3.5A);SAH A 501 (-3.1A);None;SAH A 501 (-4.2A);SAH A 501 (-3.9A);SAH A 501 (-4.3A)","0.77A","3ihtA-6gkvA:7.3","3ihtA-6gkvA:undetectable"],["3IV6_A_SAMA301_0","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"GLY A 137;SER A 162;ASP A 187;THR A 189;LEU A 205","SAH A 501 (-3.5A);None;SAH A 501 (-4.2A);None;SAH A 501 (-4.3A)","0.62A","3iv6A-6gkvA:14.1","3iv6A-6gkvA:undetectable"],["3IV6_A_SAMA301_0","PUTATIVE ZN-DEPENDENT ALCOHOL DEHYDROGENASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"SER A 162;ASP A 187;ILE A 188;THR A 189;LEU A 205","None;SAH A 501 (-4.2A);SAH A 501 (-3.9A);None;SAH A 501 (-4.3A)","0.75A","3iv6A-6gkvA:14.1","3iv6A-6gkvA:undetectable"],["3PFG_A_SAMA264_0","N-METHYLTRANSFERASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"TYR A  81;GLY A 139;SER A 162;ASP A 187;HIS A 208","SAH A 501 (-3.6A);SAH A 501 (-3.1A);None;SAH A 501 (-4.2A);SAH A 501 ( 4.6A)","0.97A","3pfgA-6gkvA:13.3","3pfgA-6gkvA:undetectable"],["4F84_A_SAMA501_0","GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"GLY A 137;GLY A 139;VAL A 159;THR A 160;GLN A 165","SAH A 501 (-3.5A);SAH A 501 (-3.1A);None;SAH A 501 ( 4.8A);SAH A 501 (-2.7A)","0.51A","4f84A-6gkvA:20.0","4f84A-6gkvA:undetectable"],["4FGZ_B_CQAB302_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",4,"GLU A 170;GLU A 167;TYR A 168;GLY A 141","None","0.96A","4fgzA-6gkvA:23.8;4fgzB-6gkvA:23.8","4fgzA-6gkvA:undetectable;4fgzB-6gkvA:undetectable"],["4IV0_B_SAMB302_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"GLY A 137;GLY A 139;ASP A 187;ILE A 188;HIS A 208","SAH A 501 (-3.5A);SAH A 501 (-3.1A);SAH A 501 (-4.2A);SAH A 501 (-3.9A);SAH A 501 ( 4.6A)","0.70A","4iv0B-6gkvA:22.5","4iv0B-6gkvA:undetectable"],["4IV0_B_SAMB302_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE, PUTATIVE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"TYR A  81;GLY A 137;GLY A 139;ASP A 187;HIS A 208","SAH A 501 (-3.6A);SAH A 501 (-3.5A);SAH A 501 (-3.1A);SAH A 501 (-4.2A);SAH A 501 ( 4.6A)","0.89A","4iv0B-6gkvA:22.5","4iv0B-6gkvA:undetectable"],["4KRH_A_SAMA900_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"TYR A  81;GLY A 137;GLY A 139;ASP A 187;HIS A 208","SAH A 501 (-3.6A);SAH A 501 (-3.5A);SAH A 501 (-3.1A);SAH A 501 (-4.2A);SAH A 501 ( 4.6A)","0.74A","4krhA-6gkvA:23.4","4krhA-6gkvA:undetectable"],["4KRH_A_SAMA900_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE 2","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"TYR A  81;GLY A 137;GLY A 139;SER A 162;ASP A 187","SAH A 501 (-3.6A);SAH A 501 (-3.5A);SAH A 501 (-3.1A);None;SAH A 501 (-4.2A)","0.94A","4krhA-6gkvA:23.4","4krhA-6gkvA:undetectable"],["4L3G_F_ACTF401_0","METHYLAMINE DEHYDROGENASE HEAVY CHAIN","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",3,"ARG A  36;LEU A  33;GLU A  37","None","0.76A","4l3gF-6gkvA:undetectable","4l3gF-6gkvA:undetectable"],["4N48_A_SAMA601_0","CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"GLY A 139;GLY A 141;THR A 160;ILE A 188;THR A 189","SAH A 501 (-3.1A);None;SAH A 501 ( 4.8A);SAH A 501 (-3.9A);None","0.78A","4n48A-6gkvA:7.4","4n48A-6gkvA:undetectable"],["4N49_A_SAMA601_0","CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"GLY A 139;GLY A 141;THR A 160;ILE A 188;THR A 189","SAH A 501 (-3.1A);None;SAH A 501 ( 4.8A);SAH A 501 (-3.9A);None","0.81A","4n49A-6gkvA:7.1","4n49A-6gkvA:undetectable"],["4PGF_A_ADNA502_1","ADENOSYLHOMOCYSTEINASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"LEU A  80;LEU A  88;ASN A  92;GLY A  98;PHE A 257","None;None;None;SAH A 501 (-3.9A);F2W A 502 (-4.5A)","1.11A","4pgfA-6gkvA:3.2","4pgfA-6gkvA:12.13"],["4ZZB_E_ACTE403_0","PROTON-GATED ION CHANNEL","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",3,"ARG A 176;TYR A 168;GLU A 172","None","0.67A","4zzbE-6gkvA:undetectable","4zzbE-6gkvA:undetectable"],["5A06_D_SORD1341_0","ALDOSE-ALDOSE OXIDOREDUCTASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",4,"CYH A 235;GLU A 347;GLY A 345;GLY A 287","None","1.01A","5a06D-6gkvA:3.1","5a06D-6gkvA:undetectable"],["5KOC_A_SAMA401_0","PAVINE N-METHYLTRANSFERASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",7,"GLY A 139;ASN A 161;GLN A 165;ASP A 187;THR A 189;LEU A 205;HIS A 208","SAH A 501 (-3.1A);SAH A 501 (-3.6A);SAH A 501 (-2.7A);SAH A 501 (-4.2A);None;SAH A 501 (-4.3A);SAH A 501 ( 4.6A)","0.66A","5kocA-6gkvA:48.5","5kocA-6gkvA:undetectable"],["5KOC_B_SAMB401_0","PAVINE N-METHYLTRANSFERASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",8,"SER A  99;GLY A 137;GLY A 139;THR A 160;ASN A 161;GLN A 165;LEU A 205;HIS A 208","SAH A 501 (-2.4A);SAH A 501 (-3.5A);SAH A 501 (-3.1A);SAH A 501 ( 4.8A);SAH A 501 (-3.6A);SAH A 501 (-2.7A);SAH A 501 (-4.3A);SAH A 501 ( 4.6A)","0.63A","5kocB-6gkvA:48.1","5kocB-6gkvA:undetectable"],["5KPC_A_SAMA401_1","PAVINE N-METHYLTRANSFERASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",4,"SER A  99;ASN A 161;GLN A 165;ASP A 187","SAH A 501 (-2.4A);SAH A 501 (-3.6A);SAH A 501 (-2.7A);SAH A 501 (-4.2A)","0.87A","5kpcA-6gkvA:47.8","5kpcA-6gkvA:undetectable"],["5KPC_B_SAMB401_0","PAVINE N-METHYLTRANSFERASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",9,"LYS A  97;SER A  99;GLY A 137;GLY A 139;ASN A 161;SER A 162;GLN A 165;ASP A 187;THR A 189","SAH A 501 ( 4.5A);SAH A 501 (-2.4A);SAH A 501 (-3.5A);SAH A 501 (-3.1A);SAH A 501 (-3.6A);None;SAH A 501 (-2.7A);SAH A 501 (-4.2A);None","0.81A","5kpcB-6gkvA:45.8","5kpcB-6gkvA:undetectable"],["5WY0_A_SAMA800_0","SMALL RNA 2'-O-METHYLTRANSFERASE","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"GLY A 137;GLY A 139;ILE A 203;LEU A 205;HIS A 208","SAH A 501 (-3.5A);SAH A 501 (-3.1A);SAH A 501 (-4.2A);SAH A 501 (-4.3A);SAH A 501 ( 4.6A)","0.51A","5wy0A-6gkvA:11.1","5wy0A-6gkvA:undetectable"],["6A7J_A_TESA502_0","CYTOCHROME P450","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",4,"LEU A  88;LEU A  96;ALA A 142;THR A 160","None;None;SAH A 501 ( 4.7A);SAH A 501 ( 4.8A)","0.79A","6a7jA-6gkvA:undetectable","6a7jA-6gkvA:23.60"],["6HWD_B_BO2B201_0","PROTEASOME SUBUNIT BETA TYPE-1;PROTEASOME SUBUNIT BETA TYPE-2","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"THR A 144;ALA A 148;GLY A 137;ALA A 158;THR A 160","None;None;SAH A 501 (-3.5A);None;SAH A 501 ( 4.8A)","1.24A","6hwdV-6gkvA:undetectable;6hwdb-6gkvA:undetectable","6hwdV-6gkvA:23.53;6hwdb-6gkvA:20.48"],["6HWD_N_BO2N201_0","PROTEASOME SUBUNIT BETA TYPE-1;PROTEASOME SUBUNIT BETA TYPE-2","6gkv","COCLAURINE N-METHYLTRANSFERASE","Coptis japonica",5,"THR A 144;ALA A 148;GLY A 137;ALA A 158;THR A 160","None;None;SAH A 501 (-3.5A);None;SAH A 501 ( 4.8A)","1.24A","6hwdH-6gkvA:undetectable;6hwdN-6gkvA:undetectable","6hwdH-6gkvA:23.53;6hwdN-6gkvA:20.48"]]