SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6glc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 6glc E3 UBIQUITIN-PROTEIN
LIGASE PARKIN
(Homo
sapiens) 		5 / 10 VAL A  56
VAL A  36
VAL A   5
ILE A   2
LEU A  26
 None
None
None
GOL  A 507 ( 4.9A)
None
 1.09A 1fe2A-6glcA:
undetectable		 1fe2A-6glcA:
11.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OK6_H_BEZH2001_0
(AROMATIC AMINE
DEHYDROGENASE, LARGE
SUBUNIT
AROMATIC AMINE
DEHYDROGENASE, SMALL
SUBUNIT)		 6glc E3 UBIQUITIN-PROTEIN
LIGASE PARKIN
(Homo
sapiens) 		5 / 10 PHE A 277
LEU A 272
GLN A 316
GLY A 319
PHE A 304
 None
 1.48A 2ok6A-6glcA:
undetectable
2ok6H-6glcA:
undetectable		 2ok6A-6glcA:
undetectable
2ok6H-6glcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z97_A_CAMA422_0
(CYTOCHROME P450-CAM)		 6glc E3 UBIQUITIN-PROTEIN
LIGASE PARKIN
(Homo
sapiens) 		4 / 6 THR A  21
VAL A  29
VAL A  67
VAL A   5
 None
 1.00A 2z97A-6glcA:
undetectable		 2z97A-6glcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 6glc E3 UBIQUITIN-PROTEIN
LIGASE PARKIN
(Homo
sapiens) 		4 / 5 ILE A 306
TYR A 267
ILE A 298
HIS A 302
 None
None
None
MPD  A 510 (-4.2A)
 1.13A 3eteB-6glcA:
undetectable
3eteC-6glcA:
undetectable		 3eteB-6glcA:
10.86
3eteC-6glcA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 6glc E3 UBIQUITIN-PROTEIN
LIGASE PARKIN
(Homo
sapiens) 		4 / 8 THR A  21
VAL A  29
VAL A  67
VAL A   5
 None
 0.88A 4l4bA-6glcA:
undetectable		 4l4bA-6glcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 6glc E3 UBIQUITIN-PROTEIN
LIGASE PARKIN
(Homo
sapiens) 		4 / 5 VAL A  30
VAL A  36
GLY A  35
PHE A   7
 None
 1.10A 5d4nA-6glcA:
undetectable
5d4nC-6glcA:
undetectable		 5d4nA-6glcA:
undetectable
5d4nC-6glcA:
undetectable