SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gmb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		4 / 7 SER A 216
ILE A 217
ILE A 213
ASP A 214
 None
 0.99A 1yc5A-6gmbA:
undetectable		 1yc5A-6gmbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		4 / 5 GLN A 350
THR A  60
THR A  64
LEU A 304
 None
 1.13A 3ce6A-6gmbA:
undetectable		 3ce6A-6gmbA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		4 / 5 GLN A 350
THR A  60
THR A  64
LEU A 304
 None
 1.13A 3ce6C-6gmbA:
undetectable		 3ce6C-6gmbA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		5 / 12 ILE A 317
VAL A  77
ILE A  75
VAL A 332
ARG A 315
 None
None
None
None
FMN  A 506 ( 3.8A)
 1.11A 3fpjB-6gmbA:
undetectable		 3fpjB-6gmbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		4 / 8 SER A 203
PHE A 175
LEU A 181
PRO A 178
 None
 1.23A 3jq7B-6gmbA:
undetectable		 3jq7B-6gmbA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		5 / 11 ILE A 233
ILE A 255
ILE A 222
ALA A 244
GLU A 246
 None
 1.05A 3tmzA-6gmbA:
undetectable		 3tmzA-6gmbA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		5 / 11 ILE A 278
ALA A 244
GLU A 283
GLY A 251
LYS A 285
 None
 1.26A 4e47A-6gmbA:
undetectable		 4e47A-6gmbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_B_SAMB800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		5 / 11 ILE A 278
ALA A 244
GLU A 283
GLY A 251
LYS A 285
 None
 1.25A 4e47B-6gmbA:
undetectable		 4e47B-6gmbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		5 / 11 ILE A 278
ALA A 244
GLU A 283
GLY A 251
LYS A 285
 None
 1.19A 4e47C-6gmbA:
undetectable		 4e47C-6gmbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_D_SAMD800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		5 / 10 ILE A 278
ALA A 244
GLU A 283
GLY A 251
LYS A 285
 None
 1.26A 4e47D-6gmbA:
undetectable		 4e47D-6gmbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J83_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		5 / 11 ILE A 278
ALA A 244
GLU A 283
GLY A 251
LYS A 285
 None
 1.25A 4j83A-6gmbA:
undetectable		 4j83A-6gmbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		5 / 11 ILE A 278
ALA A 244
GLU A 283
GLY A 251
LYS A 285
 None
 1.26A 4jdsA-6gmbA:
undetectable		 4jdsA-6gmbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		5 / 11 ILE A 278
ALA A 244
GLU A 283
GLY A 251
LYS A 285
 None
 1.24A 4jdsB-6gmbA:
undetectable		 4jdsB-6gmbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_C_SAMC401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		5 / 11 ILE A 278
ALA A 244
GLU A 283
GLY A 251
LYS A 285
 None
 1.20A 4jdsC-6gmbA:
undetectable		 4jdsC-6gmbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JDS_D_SAMD401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		5 / 11 ILE A 278
ALA A 244
GLU A 283
GLY A 251
LYS A 285
 None
 1.24A 4jdsD-6gmbA:
undetectable		 4jdsD-6gmbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		5 / 12 ILE A 278
ALA A 244
GLU A 283
GLY A 251
LYS A 285
 None
 1.19A 4jlgA-6gmbA:
undetectable		 4jlgA-6gmbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLG_B_SAMB401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		5 / 11 ILE A 278
ALA A 244
GLU A 283
GLY A 251
LYS A 285
 None
 1.17A 4jlgB-6gmbA:
undetectable		 4jlgB-6gmbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		3 / 3 ARG A 137
TRP A 224
ILE A 133
 None
 1.04A 4mwxA-6gmbA:
undetectable		 4mwxA-6gmbA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		4 / 7 PHE A 289
ASP A 291
PRO A  74
ILE A 278
 None
FMN  A 506 (-2.7A)
None
None
 0.99A 4pcuA-6gmbA:
undetectable		 4pcuA-6gmbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		5 / 11 ILE A 278
ALA A 244
GLU A 283
GLY A 251
LYS A 285
 None
 1.23A 5ayfA-6gmbA:
undetectable		 5ayfA-6gmbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		4 / 5 VAL A 294
ARG A 295
PRO A 316
GLY A 314
 None
FMN  A 506 ( 2.6A)
PG4  A 503 ( 3.7A)
FMN  A 506 (-3.4A)
 1.06A 5x80A-6gmbA:
undetectable
5x80B-6gmbA:
0.0		 5x80A-6gmbA:
18.45
5x80B-6gmbA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_2
(-)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		4 / 4 GLN A 350
THR A  60
THR A  64
LEU A 304
 None
 1.05A 6f3mB-6gmbA:
undetectable		 6f3mB-6gmbA:
11.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 6gmb HYDROXYACID OXIDASE
1
(Homo
sapiens) 		4 / 5 GLN A 350
THR A  60
THR A  64
LEU A 304
 None
 1.04A 6f3mD-6gmbA:
undetectable		 6f3mD-6gmbA:
11.34