SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gnf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6gnf -
(-) 		3 / 3 SER A 464
GLU A 465
GLU A 466
 None
 0.63A 1eqbD-6gnfA:
undetectable		 1eqbD-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6gnf -
(-) 		3 / 3 SER A 464
GLU A 465
GLU A 466
 None
 0.63A 1eqbB-6gnfA:
undetectable		 1eqbB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 6gnf -
(-) 		5 / 11 LEU A 408
VAL A 362
ILE A 349
VAL A 472
MET A 475
 None
 1.18A 1gx9A-6gnfA:
undetectable		 1gx9A-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 6gnf -
(-) 		5 / 12 ASP A 111
LEU A  20
PHE A  45
THR A  17
GLY A 102
 None
QPS  A 602 (-4.3A)
None
QPS  A 602 (-3.2A)
None
 1.20A 1ia0B-6gnfA:
3.9		 1ia0B-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_A_CCSA417_0
(ESTROGEN RECEPTOR)		 6gnf -
(-) 		3 / 3 GLU A 517
LYS A 511
VAL A 513
 None
 0.97A 1l2iA-6gnfA:
undetectable		 1l2iA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 6gnf -
(-) 		5 / 12 ASP A 111
LEU A  20
PHE A  45
THR A  17
GLY A 102
 None
QPS  A 602 (-4.3A)
None
QPS  A 602 (-3.2A)
None
 1.20A 1tubB-6gnfA:
4.3		 1tubB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6gnf -
(-) 		4 / 8 TYR A 512
TRP A 505
CYH A 416
LEU A 421
 None
None
QPS  A 602 (-4.9A)
None
 1.43A 1uw6A-6gnfA:
undetectable
1uw6B-6gnfA:
undetectable		 1uw6A-6gnfA:
undetectable
1uw6B-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6gnf -
(-) 		4 / 8 TYR A 512
TRP A 505
CYH A 416
LEU A 421
 None
None
QPS  A 602 (-4.9A)
None
 1.39A 1uw6D-6gnfA:
undetectable
1uw6E-6gnfA:
undetectable		 1uw6D-6gnfA:
undetectable
1uw6E-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6gnf -
(-) 		4 / 8 TYR A 512
TRP A 505
CYH A 416
LEU A 421
 None
None
QPS  A 602 (-4.9A)
None
 1.39A 1uw6G-6gnfA:
undetectable
1uw6H-6gnfA:
undetectable		 1uw6G-6gnfA:
undetectable
1uw6H-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6gnf -
(-) 		4 / 8 TYR A 512
TRP A 505
CYH A 416
LEU A 421
 None
None
QPS  A 602 (-4.9A)
None
 1.44A 1uw6P-6gnfA:
undetectable
1uw6Q-6gnfA:
undetectable		 1uw6P-6gnfA:
undetectable
1uw6Q-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6gnf -
(-) 		4 / 8 LEU A 421
TYR A 512
TRP A 505
CYH A 416
 None
None
None
QPS  A 602 (-4.9A)
 1.41A 1uw6P-6gnfA:
undetectable
1uw6T-6gnfA:
undetectable		 1uw6P-6gnfA:
undetectable
1uw6T-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 6gnf -
(-) 		5 / 12 ALA A 433
GLY A 344
ILE A 453
LEU A 339
ILE A 349
 None
 1.04A 1x1aA-6gnfA:
3.7		 1x1aA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ECP_A_ACRA992_1
(MALTODEXTRIN
PHOSPHORYLASE)		 6gnf -
(-) 		6 / 10 LEU A  20
TYR A 101
ASP A 108
ASP A 151
HIS A 153
ARG A 338
 QPS  A 602 (-4.3A)
QPS  A 602 (-3.9A)
QPS  A 602 ( 2.5A)
QPS  A 602 (-3.3A)
QPS  A 602 (-3.9A)
ADP  A 601 ( 4.1A)
 0.97A 2ecpA-6gnfA:
23.4		 2ecpA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ECP_B_ACRB992_1
(MALTODEXTRIN
PHOSPHORYLASE)		 6gnf -
(-) 		6 / 10 LEU A  20
TYR A 101
ASP A 108
ASP A 151
HIS A 153
ARG A 338
 QPS  A 602 (-4.3A)
QPS  A 602 (-3.9A)
QPS  A 602 ( 2.5A)
QPS  A 602 (-3.3A)
QPS  A 602 (-3.9A)
ADP  A 601 ( 4.1A)
 0.91A 2ecpB-6gnfA:
23.3		 2ecpB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 6gnf -
(-) 		3 / 3 ARG A 115
GLY A 102
PRO A 103
 None
 0.76A 2hreD-6gnfA:
2.9		 2hreD-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 6gnf -
(-) 		5 / 12 HIS A  81
PHE A  45
TYR A  14
ALA A  12
PRO A  43
 None
 1.20A 2igtC-6gnfA:
2.8		 2igtC-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_A_SAMA201_0
(UPF0066 PROTEIN
AF_0241)		 6gnf -
(-) 		5 / 12 ALA A 345
ASP A 105
ASP A 346
LEU A 339
SER A 369
 None
 1.35A 2nv4A-6gnfA:
undetectable		 2nv4A-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 6gnf -
(-) 		5 / 12 ALA A 345
ASP A 105
ASP A 346
LEU A 339
SER A 369
 None
 1.35A 2nv4B-6gnfA:
undetectable		 2nv4B-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 6gnf -
(-) 		4 / 5 LEU A 119
ALA A 117
LEU A 156
MET A 178
 None
 1.24A 2oaxA-6gnfA:
undetectable		 2oaxA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_2
(MINERALOCORTICOID
RECEPTOR)		 6gnf -
(-) 		4 / 5 LEU A 119
ALA A 117
TRP A 237
LEU A 156
 None
 1.23A 2oaxA-6gnfA:
undetectable		 2oaxA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 6gnf -
(-) 		5 / 12 LEU A 318
PHE A 335
GLY A 388
ILE A 349
ASP A 346
 None
 1.39A 2zznB-6gnfA:
undetectable		 2zznB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 6gnf -
(-) 		4 / 6 VAL A 363
LEU A 396
GLU A 321
CYH A 322
 None
 1.19A 3b6rB-6gnfA:
undetectable		 3b6rB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 6gnf -
(-) 		4 / 5 VAL A   7
VAL A  41
THR A 176
THR A   9
 None
 1.18A 3bjwA-6gnfA:
1.5		 3bjwA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 6gnf -
(-) 		4 / 5 VAL A   7
VAL A  41
THR A 176
THR A   9
 None
 1.22A 3bjwG-6gnfA:
undetectable		 3bjwG-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 6gnf -
(-) 		4 / 5 VAL A   7
VAL A  41
THR A 176
THR A   9
 None
 1.16A 3bjwC-6gnfA:
1.4		 3bjwC-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 6gnf -
(-) 		4 / 5 VAL A   7
VAL A  41
THR A 176
THR A   9
 None
 1.16A 3bjwD-6gnfA:
1.4		 3bjwD-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 6gnf -
(-) 		5 / 10 HIS A 181
VAL A 148
LEU A  27
THR A  24
VAL A  23
 QPS  A 602 (-4.1A)
None
None
None
None
 1.30A 3czvB-6gnfA:
undetectable		 3czvB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)		 6gnf -
(-) 		4 / 5 LEU A 339
GLN A 374
LEU A 376
GLU A 373
 None
 1.12A 3h5gA-6gnfA:
undetectable
3h5gB-6gnfA:
undetectable		 3h5gA-6gnfA:
undetectable
3h5gB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 6gnf -
(-) 		4 / 4 PRO A 443
THR A 441
GLY A 280
THR A 279
 None
 1.14A 3ib1A-6gnfA:
undetectable		 3ib1A-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 6gnf -
(-) 		4 / 4 GLY A  21
GLU A  10
ASP A 151
ASP A  22
 None
QPS  A 602 ( 4.5A)
QPS  A 602 (-3.3A)
ADP  A 601 ( 4.6A)
 0.89A 3mb5A-6gnfA:
4.2		 3mb5A-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 6gnf -
(-) 		5 / 12 ALA A 350
GLY A 471
ILE A 453
GLU A 465
VAL A 463
 None
 0.97A 3o7wA-6gnfA:
3.6		 3o7wA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA609_0
(GBAA_1210 PROTEIN)		 6gnf -
(-) 		3 / 3 LYS A  92
VAL A  88
HIS A  87
 None
 1.17A 3tj7A-6gnfA:
undetectable		 3tj7A-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 6gnf -
(-) 		3 / 3 TYR A 165
TYR A  71
GLN A  58
 None
 1.04A 5jsdA-6gnfA:
undetectable
5jsdB-6gnfA:
undetectable		 5jsdA-6gnfA:
undetectable
5jsdB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 6gnf -
(-) 		3 / 3 TYR A 165
TYR A  71
GLN A  58
 None
 1.03A 5jsdB-6gnfA:
undetectable
5jsdC-6gnfA:
undetectable		 5jsdB-6gnfA:
undetectable
5jsdC-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 6gnf -
(-) 		4 / 5 LEU A 197
TYR A 203
LEU A 156
TYR A 160
 None
 1.34A 5ki6A-6gnfA:
2.2		 5ki6A-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 6gnf -
(-) 		4 / 8 HIS A 181
LEU A 278
GLY A 280
VAL A 251
 QPS  A 602 (-4.1A)
None
None
QPS  A 602 ( 4.6A)
 0.83A 5m8rC-6gnfA:
undetectable		 5m8rC-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 6gnf -
(-) 		4 / 6 HIS A 181
VAL A 148
LEU A  27
THR A  24
 QPS  A 602 (-4.1A)
None
None
None
 0.89A 5ogjA-6gnfA:
undetectable		 5ogjA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 6gnf -
(-) 		4 / 6 HIS A 181
VAL A 148
LEU A  27
THR A  24
 QPS  A 602 (-4.1A)
None
None
None
 0.88A 5ogjB-6gnfA:
undetectable		 5ogjB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 6gnf -
(-) 		4 / 5 HIS A 181
VAL A 148
LEU A  27
THR A  24
 QPS  A 602 (-4.1A)
None
None
None
 0.88A 5ohhA-6gnfA:
undetectable		 5ohhA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 6gnf -
(-) 		4 / 6 HIS A 181
VAL A 148
LEU A  27
THR A  24
 QPS  A 602 (-4.1A)
None
None
None
 0.89A 5ohhB-6gnfA:
undetectable		 5ohhB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 6gnf -
(-) 		8 / 10 GLY A  19
HIS A 181
VAL A 251
ASN A 283
LYS A 343
GLU A 414
PRO A 415
GLY A 417
 ADP  A 601 ( 3.3A)
QPS  A 602 (-4.1A)
QPS  A 602 ( 4.6A)
QPS  A 602 (-3.4A)
ADP  A 601 (-2.8A)
QPS  A 602 (-3.6A)
QPS  A 602 (-3.6A)
QPS  A 602 (-3.7A)
 0.48A 5vncC-6gnfA:
21.5		 5vncC-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 6gnf -
(-) 		5 / 12 VAL A  79
THR A  24
HIS A 181
THR A  17
GLY A  18
 None
None
QPS  A 602 (-4.1A)
QPS  A 602 (-3.2A)
ADP  A 601 ( 3.8A)
 1.17A 5xipA-6gnfA:
2.8		 5xipA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 6gnf -
(-) 		5 / 12 VAL A  79
THR A  24
HIS A 181
THR A  17
GLY A  18
 None
None
QPS  A 602 (-4.1A)
QPS  A 602 (-3.2A)
ADP  A 601 ( 3.8A)
 1.15A 5xipC-6gnfA:
3.0		 5xipC-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_1
(PROLYL-TRNA
SYNTHETASE (PRORS))		 6gnf -
(-) 		3 / 3 THR A  17
GLU A  10
HIS A 153
 QPS  A 602 (-3.2A)
QPS  A 602 ( 4.5A)
QPS  A 602 (-3.9A)
 0.90A 5xiqD-6gnfA:
3.0		 5xiqD-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 6gnf -
(-) 		11 / 12 GLY A  18
GLY A  19
VAL A  23
ASP A 151
VAL A 251
ASN A 283
ARG A 338
GLN A 342
PRO A 415
CYH A 416
GLY A 417
 ADP  A 601 ( 3.8A)
ADP  A 601 ( 3.3A)
None
QPS  A 602 (-3.3A)
QPS  A 602 ( 4.6A)
QPS  A 602 (-3.4A)
ADP  A 601 ( 4.1A)
QPS  A 602 (-3.2A)
QPS  A 602 (-3.6A)
QPS  A 602 (-4.9A)
QPS  A 602 (-3.7A)
 0.42A 6gneA-6gnfA:
42.1		 6gneA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_2
(-)		 6gnf -
(-) 		5 / 6 TYR A 101
TRP A 152
HIS A 181
ASN A 182
GLU A 414
 QPS  A 602 (-3.9A)
SO4  A 606 ( 3.3A)
QPS  A 602 (-4.1A)
QPS  A 602 (-4.4A)
QPS  A 602 (-3.6A)
 0.61A 6gneA-6gnfA:
42.1		 6gneA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 6gnf -
(-) 		5 / 12 GLU A  10
GLY A  18
ASP A 151
ARG A 338
GLN A 342
 QPS  A 602 ( 4.5A)
ADP  A 601 ( 3.8A)
QPS  A 602 (-3.3A)
ADP  A 601 ( 4.1A)
QPS  A 602 (-3.2A)
 1.16A 6gneB-6gnfA:
41.8		 6gneB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 6gnf -
(-) 		11 / 12 GLU A  10
GLY A  18
GLY A  19
VAL A  23
ASP A 151
VAL A 251
ASN A 283
ARG A 338
GLN A 342
PRO A 415
GLY A 417
 QPS  A 602 ( 4.5A)
ADP  A 601 ( 3.8A)
ADP  A 601 ( 3.3A)
None
QPS  A 602 (-3.3A)
QPS  A 602 ( 4.6A)
QPS  A 602 (-3.4A)
ADP  A 601 ( 4.1A)
QPS  A 602 (-3.2A)
QPS  A 602 (-3.6A)
QPS  A 602 (-3.7A)
 0.42A 6gneB-6gnfA:
41.8		 6gneB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 6gnf -
(-) 		6 / 8 TYR A 101
TRP A 152
HIS A 181
ASN A 182
GLU A 414
CYH A 416
 QPS  A 602 (-3.9A)
SO4  A 606 ( 3.3A)
QPS  A 602 (-4.1A)
QPS  A 602 (-4.4A)
QPS  A 602 (-3.6A)
QPS  A 602 (-4.9A)
 0.63A 6gneB-6gnfA:
41.8		 6gneB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 6gnf -
(-) 		6 / 12 GLY A  19
LEU A  20
ASP A 151
HIS A 153
ASN A 182
GLN A 342
 ADP  A 601 ( 3.3A)
QPS  A 602 (-4.3A)
QPS  A 602 (-3.3A)
QPS  A 602 (-3.9A)
QPS  A 602 (-4.4A)
QPS  A 602 (-3.2A)
 0.88A 6gngA-6gnfA:
54.4		 6gngA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 6gnf -
(-) 		10 / 12 THR A  17
GLY A  18
LEU A  20
VAL A  23
ASP A 108
ASP A 151
HIS A 153
ASN A 182
ASN A 283
GLN A 342
 QPS  A 602 (-3.2A)
ADP  A 601 ( 3.8A)
QPS  A 602 (-4.3A)
None
QPS  A 602 ( 2.5A)
QPS  A 602 (-3.3A)
QPS  A 602 (-3.9A)
QPS  A 602 (-4.4A)
QPS  A 602 (-3.4A)
QPS  A 602 (-3.2A)
 0.41A 6gngA-6gnfA:
54.4		 6gngA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 6gnf -
(-) 		7 / 12 GLU A  10
GLY A  19
TYR A 101
PRO A 215
ARG A 338
GLU A 414
GLY A 417
 QPS  A 602 ( 4.5A)
ADP  A 601 ( 3.3A)
QPS  A 602 (-3.9A)
SO4  A 606 (-4.7A)
ADP  A 601 ( 4.1A)
QPS  A 602 (-3.6A)
QPS  A 602 (-3.7A)
 1.00A 6gngA-6gnfA:
54.4		 6gngA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 6gnf -
(-) 		11 / 12 GLU A  10
GLY A  19
TYR A 101
TRP A 152
HIS A 181
PRO A 216
VAL A 251
ARG A 338
GLU A 414
PRO A 415
GLY A 417
 QPS  A 602 ( 4.5A)
ADP  A 601 ( 3.3A)
QPS  A 602 (-3.9A)
SO4  A 606 ( 3.3A)
QPS  A 602 (-4.1A)
None
QPS  A 602 ( 4.6A)
ADP  A 601 ( 4.1A)
QPS  A 602 (-3.6A)
QPS  A 602 (-3.6A)
QPS  A 602 (-3.7A)
 0.34A 6gngA-6gnfA:
54.4		 6gngA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 6gnf -
(-) 		8 / 12 GLY A  19
HIS A 181
PRO A 225
VAL A 251
ARG A 338
GLU A 414
PRO A 415
GLY A 417
 ADP  A 601 ( 3.3A)
QPS  A 602 (-4.1A)
None
QPS  A 602 ( 4.6A)
ADP  A 601 ( 4.1A)
QPS  A 602 (-3.6A)
QPS  A 602 (-3.6A)
QPS  A 602 (-3.7A)
 0.77A 6gngA-6gnfA:
54.4		 6gngA-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)		 6gnf -
(-) 		6 / 12 THR A  17
VAL A  23
TYR A 101
PRO A 216
GLU A 414
GLY A 417
 QPS  A 602 (-3.2A)
None
QPS  A 602 (-3.9A)
None
QPS  A 602 (-3.6A)
QPS  A 602 (-3.7A)
 1.33A 6gngB-6gnfA:
54.2		 6gngB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_1
(-)		 6gnf -
(-) 		10 / 12 THR A  17
VAL A  23
TYR A 101
TRP A 152
HIS A 181
PRO A 215
VAL A 251
GLU A 414
CYH A 416
GLY A 417
 QPS  A 602 (-3.2A)
None
QPS  A 602 (-3.9A)
SO4  A 606 ( 3.3A)
QPS  A 602 (-4.1A)
SO4  A 606 (-4.7A)
QPS  A 602 ( 4.6A)
QPS  A 602 (-3.6A)
QPS  A 602 (-4.9A)
QPS  A 602 (-3.7A)
 0.35A 6gngB-6gnfA:
54.2		 6gngB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 6gnf -
(-) 		10 / 12 GLU A  10
GLY A  18
GLY A  19
LEU A  20
HIS A 153
ASN A 182
PRO A 216
ARG A 338
GLN A 342
PRO A 415
 QPS  A 602 ( 4.5A)
ADP  A 601 ( 3.8A)
ADP  A 601 ( 3.3A)
QPS  A 602 (-4.3A)
QPS  A 602 (-3.9A)
QPS  A 602 (-4.4A)
None
ADP  A 601 ( 4.1A)
QPS  A 602 (-3.2A)
QPS  A 602 (-3.6A)
 0.39A 6gngB-6gnfA:
54.2		 6gngB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 6gnf -
(-) 		8 / 12 GLU A  10
GLY A  18
GLY A  19
LEU A  20
PRO A 215
ARG A 338
GLN A 342
PRO A 415
 QPS  A 602 ( 4.5A)
ADP  A 601 ( 3.8A)
ADP  A 601 ( 3.3A)
QPS  A 602 (-4.3A)
SO4  A 606 (-4.7A)
ADP  A 601 ( 4.1A)
QPS  A 602 (-3.2A)
QPS  A 602 (-3.6A)
 0.92A 6gngB-6gnfA:
54.2		 6gngB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 6gnf -
(-) 		6 / 12 GLU A  10
GLY A  19
GLY A 368
ASN A 182
GLN A 342
PRO A 415
 QPS  A 602 ( 4.5A)
ADP  A 601 ( 3.3A)
None
QPS  A 602 (-4.4A)
QPS  A 602 (-3.2A)
QPS  A 602 (-3.6A)
 1.36A 6gngB-6gnfA:
54.2		 6gngB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 6gnf -
(-) 		7 / 12 GLU A  10
GLY A  19
LEU A  20
HIS A 153
ASN A 182
GLN A 342
PRO A 415
 QPS  A 602 ( 4.5A)
ADP  A 601 ( 3.3A)
QPS  A 602 (-4.3A)
QPS  A 602 (-3.9A)
QPS  A 602 (-4.4A)
QPS  A 602 (-3.2A)
QPS  A 602 (-3.6A)
 0.97A 6gngB-6gnfA:
54.2		 6gngB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 6gnf -
(-) 		7 / 12 GLY A  18
GLY A  19
ASN A 182
PRO A 225
ARG A 338
GLN A 342
PRO A 415
 ADP  A 601 ( 3.8A)
ADP  A 601 ( 3.3A)
QPS  A 602 (-4.4A)
None
ADP  A 601 ( 4.1A)
QPS  A 602 (-3.2A)
QPS  A 602 (-3.6A)
 0.74A 6gngB-6gnfA:
54.2		 6gngB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)		 6gnf -
(-) 		3 / 3 ASP A 108
ASP A 151
ASN A 283
 QPS  A 602 ( 2.5A)
QPS  A 602 (-3.3A)
QPS  A 602 (-3.4A)
 0.33A 6gngB-6gnfA:
54.2		 6gngB-6gnfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 6gnf -
(-) 		4 / 6 VAL A 251
ASN A 254
PRO A 253
GLU A 258
 QPS  A 602 ( 4.6A)
None
None
None
 1.18A 6h7uA-6gnfA:
undetectable		 6h7uA-6gnfA:
undetectable