SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gpc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 6gpc -
(-) 		5 / 9 LEU A  46
ILE A  42
ARG A   8
VAL A 108
LEU A 115
 None
 1.19A 1e7aB-6gpcA:
undetectable		 1e7aB-6gpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 6gpc -
(-) 		5 / 11 SER A  16
GLY A  14
VAL A  53
SER A  74
ILE A  69
 ARG  A 301 (-3.9A)
None
None
ARG  A 301 (-3.0A)
None
 1.23A 1pk9C-6gpcA:
undetectable		 1pk9C-6gpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q8H_A_TF4A438_1
([PYRUVATE
DEHYDROGENASE
[LIPOAMIDE]] KINASE
ISOZYME 1)		 6gpc -
(-) 		4 / 6 LEU A  38
TYR A  92
ILE A 119
ILE A  73
 None
 0.82A 2q8hA-6gpcA:
undetectable		 2q8hA-6gpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 6gpc -
(-) 		5 / 12 LEU A 126
LEU A  38
ARG A 124
LEU A  11
VAL A  13
 None
 1.33A 2qd4A-6gpcA:
undetectable		 2qd4A-6gpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 6gpc -
(-) 		4 / 8 ASP A  94
GLY A  96
TYR A 104
PRO A  91
 None
None
ARG  A 301 (-4.3A)
None
 1.00A 3s3nA-6gpcA:
undetectable		 3s3nA-6gpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 6gpc -
(-) 		5 / 12 LEU A  46
ILE A  78
LEU A 123
VAL A 122
ILE A  73
 None
 1.28A 3sp9A-6gpcA:
undetectable		 3sp9A-6gpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 6gpc -
(-) 		5 / 10 LEU A  12
VAL A  13
GLU A  49
VAL A  48
ILE A   5
 None
 1.08A 5v02B-6gpcA:
undetectable
5v02R-6gpcA:
undetectable		 5v02B-6gpcA:
undetectable
5v02R-6gpcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 6gpc -
(-) 		5 / 9 LEU A  11
VAL A  71
SER A 121
LEU A 123
ILE A 106
 None
 1.42A 6fdyU-6gpcA:
undetectable		 6fdyU-6gpcA:
undetectable