SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gqd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE
(Homo
sapiens) 		4 / 4 ARG A  33
ALA A 247
ALA A 354
GLU A 352
 None
 1.12A 1e7bA-6gqdA:
undetectable		 1e7bA-6gqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE
(Homo
sapiens) 		4 / 4 ARG A  33
ALA A 247
ALA A 354
GLU A 352
 None
 1.12A 1e7bB-6gqdA:
undetectable		 1e7bB-6gqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE
(Homo
sapiens) 		4 / 5 ARG A  33
ALA A 247
ALA A 354
GLU A 352
 None
 1.20A 1e7cA-6gqdA:
undetectable		 1e7cA-6gqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_C_ADNC2502_2
(ADENOSYLHOMOCYSTEINA
SE)		 6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE
(Homo
sapiens) 		3 / 3 GLU A 159
THR A 158
LEU A 318
 None
 0.72A 1v8bC-6gqdA:
undetectable		 1v8bC-6gqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE
(Homo
sapiens) 		4 / 6 ARG A 262
THR A 305
ALA A 309
ARG A 263
 None
 1.36A 2ql8A-6gqdA:
undetectable
2ql8B-6gqdA:
undetectable		 2ql8A-6gqdA:
undetectable
2ql8B-6gqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE
(Homo
sapiens) 		3 / 3 TRP A 154
VAL A 168
TRP A 300
 None
 1.22A 2xdcC-6gqdA:
undetectable
2xdcD-6gqdA:
undetectable		 2xdcC-6gqdA:
undetectable
2xdcD-6gqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE
(Homo
sapiens) 		3 / 3 TRP A 154
VAL A 168
TRP A 300
 None
 1.19A 2xdcE-6gqdA:
undetectable
2xdcF-6gqdA:
undetectable		 2xdcE-6gqdA:
undetectable
2xdcF-6gqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE
(Homo
sapiens) 		3 / 3 TRP A 154
VAL A 168
TRP A 300
 None
 1.20A 2y5mE-6gqdA:
undetectable
2y5mF-6gqdA:
undetectable		 2y5mE-6gqdA:
undetectable
2y5mF-6gqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE
(Homo
sapiens) 		3 / 3 TRP A 154
VAL A 168
TRP A 300
 None
 1.20A 2y6nC-6gqdA:
undetectable
2y6nD-6gqdA:
undetectable		 2y6nC-6gqdA:
undetectable
2y6nD-6gqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE
(Homo
sapiens) 		3 / 3 TRP A 154
VAL A 168
TRP A 300
 None
 1.22A 2y6nE-6gqdA:
undetectable
2y6nF-6gqdA:
undetectable		 2y6nE-6gqdA:
undetectable
2y6nF-6gqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_B_DVAB8_0
(VAL-GRAMICIDIN A)		 6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE
(Homo
sapiens) 		3 / 3 TRP A 154
VAL A 168
TRP A 300
 None
 1.44A 3zq8A-6gqdA:
undetectable
3zq8B-6gqdA:
undetectable		 3zq8A-6gqdA:
undetectable
3zq8B-6gqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE
(Homo
sapiens) 		4 / 5 THR A 235
LEU A 234
GLU A 363
LYS A 285
 None
 1.24A 4a3pA-6gqdA:
undetectable		 4a3pA-6gqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE
(Homo
sapiens) 		6 / 12 PHE A 131
TRP A 154
LEU A 139
ILE A 278
TYR A 296
LEU A 255
 None
 1.28A 5ienB-6gqdA:
undetectable		 5ienB-6gqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KI6_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE
(Homo
sapiens) 		4 / 5 ARG A 201
GLN A 200
PRO A 196
ILE A 198
 None
 1.44A 5ki6A-6gqdA:
undetectable		 5ki6A-6gqdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 6gqd GALACTOSE-1-PHOSPHAT
E
URIDYLYLTRANSFERASE
(Homo
sapiens) 		4 / 8 GLU A  40
ILE A 198
TRP A 167
TRP A 316
 None
 1.07A 5vlmD-6gqdA:
undetectable		 5vlmD-6gqdA:
undetectable