SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gqz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 6gqz -
(-) 		4 / 8 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
 0.95A 1sn5C-6gqzA:
undetectable		 1sn5C-6gqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 6gqz -
(-) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 1.02A 1t87A-6gqzA:
undetectable		 1t87A-6gqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 6gqz -
(-) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 1.00A 2feuB-6gqzA:
undetectable		 2feuB-6gqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 6gqz -
(-) 		4 / 6 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 1.06A 2zuhA-6gqzA:
undetectable		 2zuhA-6gqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 6gqz -
(-) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 0.98A 2zwtA-6gqzA:
undetectable		 2zwtA-6gqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 6gqz -
(-) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 1.02A 3fwfA-6gqzA:
undetectable		 3fwfA-6gqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 6gqz -
(-) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 1.03A 3fwfB-6gqzA:
undetectable		 3fwfB-6gqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L63_A_CAMA440_0
(CAMPHOR
5-MONOOXYGENASE)		 6gqz -
(-) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 1.02A 3l63A-6gqzA:
undetectable		 3l63A-6gqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 6gqz -
(-) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 0.98A 3wrhA-6gqzA:
undetectable		 3wrhA-6gqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 6gqz -
(-) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 1.00A 3wrjA-6gqzA:
undetectable		 3wrjA-6gqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 6gqz -
(-) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 1.00A 3wrlA-6gqzA:
undetectable		 3wrlA-6gqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 6gqz -
(-) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 0.99A 3wrmA-6gqzA:
undetectable		 3wrmA-6gqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 6gqz -
(-) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 1.01A 3wrmF-6gqzA:
undetectable		 3wrmF-6gqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 6gqz -
(-) 		4 / 8 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
 0.98A 4ik6B-6gqzA:
undetectable		 4ik6B-6gqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 6gqz -
(-) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 1.01A 4l4gA-6gqzA:
undetectable		 4l4gA-6gqzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIG_A_EDTA501_0
(ADENOSINE RECEPTOR
A2A,SOLUBLE
CYTOCHROME
B562,ADENOSINE
RECEPTOR A2A)		 6gqz -
(-) 		4 / 6 ASN A  72
THR A  77
ARG A  79
ILE A  52
 None
 1.28A 5uigA-6gqzA:
undetectable		 5uigA-6gqzA:
undetectable