SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6grw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 6grw -
(-) 		5 / 11 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.94A 1hxwB-6grwA:
undetectable		 1hxwB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)		 6grw -
(-) 		5 / 10 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.80A 1t3rA-6grwA:
undetectable		 1t3rA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_1
(POL POLYPROTEIN)		 6grw -
(-) 		5 / 10 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.85A 1t7iA-6grwA:
undetectable		 1t7iA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 6grw -
(-) 		3 / 3 ALA A 214
VAL A 216
TRP A 219
 None
 0.69A 1tkqA-6grwA:
undetectable		 1tkqA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 6grw -
(-) 		4 / 7 TYR A 418
GLU A 290
HIS A 408
GLY A 409
 None
 1.24A 2ha4B-6grwA:
14.4		 2ha4B-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 6grw -
(-) 		5 / 9 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.82A 2idwB-6grwA:
undetectable		 2idwB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_2
(PROTEASE)		 6grw -
(-) 		5 / 12 LEU A 137
ALA A 276
VAL A 286
VAL A 261
VAL A 263
 None
 0.86A 2ieoB-6grwA:
undetectable		 2ieoB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_2
(PROTEASE)		 6grw -
(-) 		5 / 11 LEU A 137
ALA A 276
VAL A 286
VAL A 261
VAL A 263
 None
 0.95A 2nnpB-6grwA:
undetectable		 2nnpB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 6grw -
(-) 		4 / 4 ALA A 113
VAL A  83
PHE A 107
THR A 104
 None
 1.41A 2pkkA-6grwA:
3.0		 2pkkA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 6grw -
(-) 		5 / 12 VAL A 238
GLY A 202
ILE A 160
SER A 156
TRP A 159
 None
 1.46A 3bwmA-6grwA:
undetectable		 3bwmA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_0
(COMT PROTEIN)		 6grw -
(-) 		5 / 12 VAL A 238
GLY A 202
ILE A 160
SER A 156
TRP A 159
 None
 1.46A 3bwyA-6grwA:
undetectable		 3bwyA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 6grw -
(-) 		5 / 9 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.87A 3ektA-6grwA:
undetectable		 3ektA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 6grw -
(-) 		5 / 10 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.88A 3ekvA-6grwA:
undetectable		 3ekvA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 6grw -
(-) 		5 / 11 ASP A 414
ILE A 287
GLY A 265
LEU A 269
VAL A 196
 None
 0.91A 3em4U-6grwA:
undetectable		 3em4U-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 6grw -
(-) 		5 / 9 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.89A 3gguB-6grwA:
undetectable		 3gguB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 6grw -
(-) 		3 / 3 PRO A 134
PHE A 136
ALA A 422
 None
 0.61A 3itaD-6grwA:
undetectable		 3itaD-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 6grw -
(-) 		5 / 10 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.83A 3lzvA-6grwA:
undetectable		 3lzvA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)		 6grw -
(-) 		5 / 9 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.94A 3nujB-6grwA:
undetectable		 3nujB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)		 6grw -
(-) 		5 / 9 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.94A 3nuoB-6grwA:
undetectable		 3nuoB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 6grw -
(-) 		5 / 12 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.93A 3ogqB-6grwA:
undetectable		 3ogqB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 6grw -
(-) 		5 / 10 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.81A 3oy4B-6grwA:
undetectable		 3oy4B-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 6grw -
(-) 		4 / 6 LEU A  62
LEU A  65
PRO A  37
LEU A 332
 None
 0.89A 3q1eA-6grwA:
undetectable
3q1eC-6grwA:
undetectable		 3q1eA-6grwA:
undetectable
3q1eC-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q1E_C_T44C128_1
(5-HYDROXYISOURATE
HYDROLASE)		 6grw -
(-) 		4 / 6 PRO A  37
LEU A 332
LEU A  62
LEU A  65
 None
 0.79A 3q1eA-6grwA:
undetectable
3q1eC-6grwA:
undetectable		 3q1eA-6grwA:
undetectable
3q1eC-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 6grw -
(-) 		5 / 9 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.91A 3u7sA-6grwA:
undetectable		 3u7sA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)		 6grw -
(-) 		5 / 12 GLY A 138
LEU A 139
ALA A 422
PHE A 283
LEU A 285
 None
None
None
None
EDO  A 509 ( 4.9A)
 1.26A 3vywB-6grwA:
undetectable		 3vywB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1002_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 6grw -
(-) 		3 / 3 ASN A 140
TRP A 184
ASP A 203
 None
 0.94A 4a7tA-6grwA:
undetectable
4a7tF-6grwA:
undetectable		 4a7tA-6grwA:
undetectable
4a7tF-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 6grw -
(-) 		5 / 10 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.81A 4dqbB-6grwA:
undetectable		 4dqbB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 6grw -
(-) 		5 / 9 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.83A 4dqcB-6grwA:
undetectable		 4dqcB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 6grw -
(-) 		5 / 10 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.83A 4dqeB-6grwA:
undetectable		 4dqeB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 6grw -
(-) 		5 / 10 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.81A 4dqhB-6grwA:
undetectable		 4dqhB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_B_15UB402_1
(PROTHROMBIN)		 6grw -
(-) 		5 / 12 ALA A 297
ILE A 236
GLU A 364
GLY A 270
GLY A 265
 CA  A 503 ( 4.9A)
None
None
None
None
 1.27A 4hfpB-6grwA:
undetectable		 4hfpB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 6grw -
(-) 		5 / 12 PRO A 407
GLU A 290
HIS A 266
SER A 267
GLY A 292
 None
 1.13A 4hvcA-6grwA:
undetectable		 4hvcA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 6grw -
(-) 		5 / 12 PRO A 407
GLU A 290
HIS A 266
SER A 267
GLY A 292
 None
 1.16A 4hvcB-6grwA:
undetectable		 4hvcB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 6grw -
(-) 		5 / 10 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.88A 4ll3B-6grwA:
undetectable		 4ll3B-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_2
(PROTEASE)		 6grw -
(-) 		5 / 10 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.86A 4njtB-6grwA:
undetectable		 4njtB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 6grw -
(-) 		5 / 12 PRO A 407
GLU A 290
HIS A 266
SER A 267
GLY A 292
 None
 1.11A 4olfA-6grwA:
undetectable		 4olfA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 6grw -
(-) 		5 / 11 LEU A 190
ALA A  98
LEU A  94
VAL A 147
HIS A 148
 None
 1.14A 4p65C-6grwA:
undetectable
4p65D-6grwA:
undetectable
4p65J-6grwA:
undetectable
4p65L-6grwA:
undetectable		 4p65C-6grwA:
undetectable
4p65D-6grwA:
undetectable
4p65J-6grwA:
undetectable
4p65L-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 6grw -
(-) 		5 / 11 LEU A 118
LEU A 204
LEU A 137
LEU A 243
ALA A 246
 None
 1.01A 4p65B-6grwA:
undetectable
4p65D-6grwA:
undetectable
4p65G-6grwA:
undetectable
4p65H-6grwA:
undetectable		 4p65B-6grwA:
undetectable
4p65D-6grwA:
undetectable
4p65G-6grwA:
undetectable
4p65H-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 6grw -
(-) 		5 / 9 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.83A 4q1wA-6grwA:
undetectable		 4q1wA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 6grw -
(-) 		5 / 10 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.83A 4q1yA-6grwA:
undetectable		 4q1yA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 6grw -
(-) 		3 / 3 MET A  89
ASP A 253
PHE A  84
 None
 0.99A 4xeyA-6grwA:
undetectable		 4xeyA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 6grw -
(-) 		3 / 3 MET A  89
ASP A 253
PHE A  84
 None
 0.93A 4xeyB-6grwA:
undetectable		 4xeyB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_B_SAMB303_0
(CATECHOL
O-METHYLTRANSFERASE)		 6grw -
(-) 		5 / 12 VAL A 238
GLY A 202
ILE A 160
SER A 156
TRP A 159
 None
 1.44A 4xueB-6grwA:
undetectable		 4xueB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 6grw -
(-) 		5 / 12 PRO A 407
GLU A 290
HIS A 266
SER A 267
GLY A 292
 None
 1.17A 4ydqA-6grwA:
undetectable		 4ydqA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 6grw -
(-) 		5 / 12 PRO A 407
GLU A 290
HIS A 266
SER A 267
GLY A 292
 None
 1.17A 4ydqB-6grwA:
2.0		 4ydqB-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_A_FOLA201_0
(FOLATE ECF
TRANSPORTER)		 6grw -
(-) 		5 / 12 LEU A 274
LYS A 271
SER A 267
ALA A 235
PHE A 318
 None
 1.28A 4z7fA-6grwA:
undetectable		 4z7fA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZO1_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA)		 6grw -
(-) 		5 / 12 ALA A 276
ALA A 246
ARG A 245
HIS A 264
MET A 410
 None
 1.42A 4zo1X-6grwA:
undetectable		 4zo1X-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 6grw -
(-) 		5 / 9 LEU A 247
GLY A 277
ALA A 276
GLY A 265
ILE A 287
 None
 0.92A 5kr0B-6grwA:
undetectable		 5kr0B-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 6grw -
(-) 		5 / 12 VAL A 238
GLY A 202
ILE A 160
SER A 156
TRP A 159
 None
 1.47A 5lsaA-6grwA:
undetectable		 5lsaA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_A_HFGA801_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 6grw -
(-) 		5 / 12 PRO A 407
GLU A 290
HIS A 266
SER A 267
GLY A 292
 None
 1.19A 5xioA-6grwA:
2.2		 5xioA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 6grw -
(-) 		5 / 12 PRO A 407
GLU A 290
HIS A 266
SER A 267
GLY A 292
 None
 1.09A 5xiqA-6grwA:
undetectable		 5xiqA-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 6grw -
(-) 		5 / 11 TYR A 121
VAL A 196
ALA A 276
ASN A 144
VAL A 199
 None
 1.35A 6hu9A-6grwA:
undetectable
6hu9E-6grwA:
undetectable
6hu9I-6grwA:
undetectable		 6hu9A-6grwA:
undetectable
6hu9E-6grwA:
undetectable
6hu9I-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 6grw -
(-) 		5 / 10 TYR A 121
VAL A 196
ALA A 276
ASN A 144
VAL A 199
 None
 1.33A 6hu9L-6grwA:
undetectable
6hu9P-6grwA:
undetectable
6hu9T-6grwA:
undetectable		 6hu9L-6grwA:
undetectable
6hu9P-6grwA:
undetectable
6hu9T-6grwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_HFGA603_0
(UNCHARACTERIZED
PROTEIN)		 6grw -
(-) 		5 / 12 PRO A 407
GLU A 290
HIS A 266
SER A 267
GLY A 292
 None
 1.16A 6mn8A-6grwA:
undetectable		 6mn8A-6grwA:
undetectable