SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gww'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		4 / 8 PRO A  42
THR A  46
PRO A  47
ARG A 125
 CSO  A  49 ( 4.0A)
CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.1A)
 0.52A 1h4oB-6gwwA:
18.3		 1h4oB-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		4 / 8 PRO A  42
THR A  46
PRO A  47
ARG A 125
 CSO  A  49 ( 4.0A)
CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.1A)
 0.52A 1oc3A-6gwwA:
18.2		 1oc3A-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		5 / 10 LEU A 154
ALA A 156
ILE A 157
VAL A 127
PHE A  63
 None
 1.11A 1xp0A-6gwwA:
undetectable		 1xp0A-6gwwA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		5 / 12 ILE A 153
ILE A 157
ALA A 156
ARG A 155
ILE A   9
 None
 1.11A 1xzxX-6gwwA:
undetectable		 1xzxX-6gwwA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		4 / 4 GLY A  43
SER A  74
ILE A 100
HIS A  81
 None
 1.29A 1yajJ-6gwwA:
undetectable		 1yajJ-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_A_BEZA1222_0
(PEROXIREDOXIN 6)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		4 / 7 THR A  46
PRO A  47
VAL A  48
ARG A 125
 CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.0A)
CSO  A  49 ( 3.1A)
 0.23A 2v2gA-6gwwA:
24.5
2v2gB-6gwwA:
24.5		 2v2gA-6gwwA:
undetectable
2v2gB-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_B_BEZB1220_0
(PEROXIREDOXIN 6)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		4 / 7 THR A  46
PRO A  47
VAL A  48
ARG A 125
 CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.0A)
CSO  A  49 ( 3.1A)
 0.22A 2v2gA-6gwwA:
24.5
2v2gB-6gwwA:
24.5		 2v2gA-6gwwA:
undetectable
2v2gB-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_C_BEZC1222_0
(PEROXIREDOXIN 6)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		4 / 7 THR A  46
PRO A  47
VAL A  48
ARG A 125
 CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.0A)
CSO  A  49 ( 3.1A)
 0.23A 2v2gC-6gwwA:
24.5
2v2gD-6gwwA:
24.5		 2v2gC-6gwwA:
undetectable
2v2gD-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V2G_D_BEZD1221_0
(PEROXIREDOXIN 6)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		4 / 7 THR A  46
PRO A  47
VAL A  48
ARG A 125
 CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.0A)
CSO  A  49 ( 3.1A)
 0.20A 2v2gC-6gwwA:
24.5
2v2gD-6gwwA:
24.5		 2v2gC-6gwwA:
undetectable
2v2gD-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		5 / 8 PRO A  42
THR A  46
PRO A  47
VAL A  48
ARG A 125
 CSO  A  49 ( 4.0A)
CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.0A)
CSO  A  49 ( 3.1A)
 0.21A 2v32C-6gwwA:
24.4
2v32D-6gwwA:
26.2		 2v32C-6gwwA:
undetectable
2v32D-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_D_BEZD1221_0
(PEROXIREDOXIN 6)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		4 / 8 THR A  46
PRO A  47
VAL A  48
ARG A 125
 CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.0A)
CSO  A  49 ( 3.1A)
 0.25A 2v32C-6gwwA:
24.4
2v32D-6gwwA:
26.2		 2v32C-6gwwA:
undetectable
2v32D-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_A_BEZA1222_0
(PEROXIREDOXIN 6.)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		5 / 9 PRO A  42
THR A  46
PRO A  47
VAL A  48
ARG A 125
 CSO  A  49 ( 4.0A)
CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.0A)
CSO  A  49 ( 3.1A)
 0.23A 2v41A-6gwwA:
24.3
2v41B-6gwwA:
24.4		 2v41A-6gwwA:
undetectable
2v41B-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_B_BEZB1222_0
(PEROXIREDOXIN 6.)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		5 / 9 PRO A  42
THR A  46
PRO A  47
VAL A  48
ARG A 125
 CSO  A  49 ( 4.0A)
CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.0A)
CSO  A  49 ( 3.1A)
 0.25A 2v41A-6gwwA:
24.4
2v41B-6gwwA:
24.4		 2v41A-6gwwA:
undetectable
2v41B-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		5 / 8 PRO A  42
THR A  46
PRO A  47
VAL A  48
ARG A 125
 CSO  A  49 ( 4.0A)
CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.0A)
CSO  A  49 ( 3.1A)
 0.26A 2v41C-6gwwA:
26.2
2v41D-6gwwA:
26.5		 2v41C-6gwwA:
undetectable
2v41D-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		5 / 8 PRO A  42
THR A  46
PRO A  47
VAL A  48
ARG A 125
 CSO  A  49 ( 4.0A)
CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.0A)
CSO  A  49 ( 3.1A)
 0.22A 2v41C-6gwwA:
26.2
2v41D-6gwwA:
26.5		 2v41C-6gwwA:
undetectable
2v41D-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_E_BEZE1222_0
(PEROXIREDOXIN 6.)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		4 / 7 THR A  46
PRO A  47
VAL A  48
ARG A 125
 CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.0A)
CSO  A  49 ( 3.1A)
 0.31A 2v41E-6gwwA:
24.3
2v41F-6gwwA:
24.4		 2v41E-6gwwA:
undetectable
2v41F-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_F_BEZF1222_0
(PEROXIREDOXIN 6.)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		4 / 7 THR A  46
PRO A  47
VAL A  48
ARG A 125
 CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.0A)
CSO  A  49 ( 3.1A)
 0.31A 2v41E-6gwwA:
24.3
2v41F-6gwwA:
24.4		 2v41E-6gwwA:
undetectable
2v41F-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_G_BEZG1222_0
(PEROXIREDOXIN 6.)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		4 / 8 THR A  46
PRO A  47
VAL A  48
ARG A 125
 CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.0A)
CSO  A  49 ( 3.1A)
 0.28A 2v41G-6gwwA:
24.4
2v41H-6gwwA:
24.4		 2v41G-6gwwA:
undetectable
2v41H-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		5 / 8 PRO A  42
THR A  46
PRO A  47
VAL A  48
ARG A 125
 CSO  A  49 ( 4.0A)
CSO  A  49 ( 3.3A)
None
CSO  A  49 ( 3.0A)
CSO  A  49 ( 3.1A)
 0.21A 2v41G-6gwwA:
24.4
2v41H-6gwwA:
24.4		 2v41G-6gwwA:
undetectable
2v41H-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLJ_A_SPMA1303_1
(POTASSIUM CHANNEL)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		3 / 3 ARG A 155
ARG A 158
PRO A 175
 None
 1.13A 2wljA-6gwwA:
undetectable		 2wljA-6gwwA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		5 / 12 ILE A   9
ARG A 137
ILE A  71
GLU A  69
ASP A 131
 None
 1.16A 3axtA-6gwwA:
undetectable		 3axtA-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_A_VDNA1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		5 / 12 LEU A 154
ALA A 156
ILE A 157
VAL A 127
PHE A  63
 None
 1.07A 3b2rA-6gwwA:
undetectable		 3b2rA-6gwwA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B2R_B_VDNB1_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		5 / 11 LEU A 154
ALA A 156
ILE A 157
VAL A 127
PHE A  63
 None
 1.10A 3b2rB-6gwwA:
undetectable		 3b2rB-6gwwA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		4 / 5 PHE A  98
TYR A  54
LEU A  66
LYS A  64
 None
 1.42A 3sudD-6gwwA:
undetectable		 3sudD-6gwwA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		5 / 9 ASN A  78
ALA A 102
ASP A  76
GLY A  72
ILE A  71
 None
 1.09A 5kr2A-6gwwA:
undetectable		 5kr2A-6gwwA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_1
(PROTEASE PR5-SQV)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		5 / 9 ASN A  78
ALA A 102
ASP A  76
GLY A  72
ILE A  71
 None
 1.24A 5kr2C-6gwwA:
undetectable		 5kr2C-6gwwA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_A_CUA601_0
(THIOCYANATE
DEHYDROGENASE)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		3 / 3 HIS A  41
ASP A  44
HIS A  81
 CSO  A  49 ( 4.4A)
None
None
 0.78A 5oexA-6gwwA:
undetectable		 5oexA-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		3 / 3 HIS A  41
ASP A  44
HIS A  81
 CSO  A  49 ( 4.4A)
None
None
 0.76A 5oexB-6gwwA:
undetectable		 5oexB-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		3 / 3 HIS A  41
ASP A  44
HIS A  81
 CSO  A  49 ( 4.4A)
None
None
 0.74A 5oexC-6gwwA:
undetectable		 5oexC-6gwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 6gww PEROXIREDOXIN
(Sulfolobus
islandicus) 		3 / 3 HIS A  41
ASP A  44
HIS A  81
 CSO  A  49 ( 4.4A)
None
None
 0.75A 5oexD-6gwwA:
undetectable		 5oexD-6gwwA:
undetectable