SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gxz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 6gxz -
(-) 		5 / 12 GLY A 308
ASN A 321
ARG A 322
ASP A 312
ALA A 311
 None
 1.19A 2br4B-6gxzA:
undetectable		 2br4B-6gxzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 6gxz -
(-) 		5 / 9 LEU D 255
VAL D 281
ILE D 259
LEU D 220
ILE D 239
 None
 1.03A 3jw3B-6gxzD:
undetectable		 3jw3B-6gxzD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WEA_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 6gxz -
(-) 		4 / 5 TYR A 349
LYS A 351
LEU A 379
GLU A 380
 None
 1.17A 5weaA-6gxzA:
undetectable		 5weaA-6gxzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 6gxz -
(-) 		4 / 6 VAL D 281
ASN D 264
PRO D 284
ILE D 263
 None
 1.08A 6h7uA-6gxzD:
undetectable		 6h7uA-6gxzD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 6gxz -
(-) 		4 / 7 ARG A 356
ALA A 354
ILE A 343
ALA A 342
 None
 0.86A 6ma7A-6gxzA:
undetectable		 6ma7A-6gxzA:
undetectable