SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gy6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 6gy6 -
(-) 		3 / 3 ALA B 312
VAL B 307
TRP B 308
 None
 0.89A 1nrmA-6gy6B:
undetectable		 1nrmA-6gy6B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 6gy6 -
(-) 		3 / 3 ALA B 312
VAL B 307
TRP B 308
 None
 0.89A 1nrmB-6gy6B:
undetectable		 1nrmB-6gy6B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 6gy6 -
(-) 		3 / 3 ALA B 312
VAL B 307
TRP B 308
 None
 0.88A 1nruA-6gy6B:
undetectable		 1nruA-6gy6B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 6gy6 -
(-) 		3 / 3 ALA B 312
VAL B 307
TRP B 308
 None
 0.88A 1nruB-6gy6B:
undetectable		 1nruB-6gy6B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 6gy6 -
(-) 		5 / 12 ILE B  16
ALA B 301
LEU B 132
SER B  63
LEU B 339
 None
 1.09A 3eigA-6gy6B:
undetectable		 3eigA-6gy6B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 6gy6 -
(-) 		5 / 11 HIS B 117
PHE B 311
VAL B 121
LEU B  71
THR B  75
 None
 1.21A 3ml5A-6gy6B:
undetectable		 3ml5A-6gy6B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 6gy6 -
(-) 		3 / 3 LYS B 172
LYS B 169
PRO B 168
 None
 1.02A 4dv1L-6gy6B:
undetectable		 4dv1L-6gy6B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_B_MXMB606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6gy6 -
(-) 		5 / 12 VAL B 121
LEU B  71
ALA B 312
LEU B 315
LEU B 331
 None
 0.92A 4m11B-6gy6B:
undetectable		 4m11B-6gy6B:
undetectable