SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6gy8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NH8_A_HISA289_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 6gy8 -
(-) 		4 / 5 ASP A  96
LEU A 216
ALA A  98
LEU A  99
 None
 1.14A 1nh8A-6gy8A:
undetectable		 1nh8A-6gy8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 6gy8 -
(-) 		5 / 12 PHE A 359
VAL A 378
ILE A 133
ILE A 130
LEU A 174
 None
 1.16A 2ft9A-6gy8A:
undetectable		 2ft9A-6gy8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 6gy8 -
(-) 		4 / 8 TYR A 159
ASN A 161
ASP A 162
ASP A 163
 None
 1.04A 4f8hA-6gy8A:
4.8
4f8hB-6gy8A:
4.9		 4f8hA-6gy8A:
undetectable
4f8hB-6gy8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 6gy8 -
(-) 		4 / 8 TYR A 159
ASN A 161
ASP A 162
ASP A 163
 None
 1.04A 4f8hB-6gy8A:
4.9
4f8hC-6gy8A:
4.8		 4f8hB-6gy8A:
undetectable
4f8hC-6gy8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 6gy8 -
(-) 		4 / 8 TYR A 159
ASN A 161
ASP A 162
ASP A 163
 None
 1.04A 4f8hD-6gy8A:
4.9
4f8hE-6gy8A:
4.8		 4f8hD-6gy8A:
undetectable
4f8hE-6gy8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 6gy8 -
(-) 		4 / 8 TYR A 159
ASN A 161
ASP A 162
ASP A 163
 None
 1.04A 4f8hA-6gy8A:
4.8
4f8hE-6gy8A:
4.8		 4f8hA-6gy8A:
undetectable
4f8hE-6gy8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 6gy8 -
(-) 		4 / 7 ALA A  98
ILE A  51
LEU A 202
PHE A 198
 None
 1.00A 4uymA-6gy8A:
undetectable		 4uymA-6gy8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 6gy8 -
(-) 		4 / 7 ALA A  98
ILE A  51
LEU A 202
PHE A 198
 None
 0.99A 4uymB-6gy8A:
undetectable		 4uymB-6gy8A:
undetectable