SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6h20'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 6h20 -
(-) 		4 / 8 GLN A 184
ILE A 226
VAL A 205
PRO A 224
 None
 0.90A 1rxcB-6h20A:
undetectable		 1rxcB-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 6h20 -
(-) 		4 / 7 GLN A 184
ILE A 226
VAL A 205
PRO A 224
 None
 0.91A 1rxcF-6h20A:
undetectable		 1rxcF-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 6h20 -
(-) 		4 / 8 GLN A 184
ILE A 226
VAL A 205
PRO A 224
 None
 0.91A 1rxcK-6h20A:
undetectable		 1rxcK-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XKK_A_FMMA91_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 6h20 -
(-) 		6 / 12 ALA A 144
THR A 211
GLY A 101
LEU A 104
THR A 249
ASP A 250
 ASN  A 401 ( 4.3A)
ASN  A 401 (-4.0A)
None
None
ASN  A 401 ( 4.9A)
ASN  A 401 (-2.9A)
 1.27A 1xkkA-6h20A:
undetectable		 1xkkA-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 6h20 -
(-) 		3 / 3 ARG A 325
ASP A 181
ASP A 250
 None
None
ASN  A 401 (-2.9A)
 0.85A 2ejtA-6h20A:
undetectable		 2ejtA-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 6h20 -
(-) 		3 / 3 LEU A  42
PRO A  43
ARG A 242
 None
 0.53A 2qd4B-6h20A:
undetectable		 2qd4B-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 6h20 -
(-) 		3 / 3 LEU A  42
PRO A  43
ARG A 242
 None
 0.38A 2qd5A-6h20A:
undetectable		 2qd5A-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 6h20 -
(-) 		5 / 12 SER A 102
GLY A 101
GLY A  97
ASP A 157
VAL A 156
 None
 1.02A 3gczA-6h20A:
undetectable		 3gczA-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 6h20 -
(-) 		5 / 12 LEU A 180
ASP A 250
ALA A 208
ARG A 147
ARG A 169
 None
ASN  A 401 (-2.9A)
None
ASN  A 401 (-3.0A)
ASN  A 401 (-2.9A)
 1.40A 3k39D-6h20A:
undetectable		 3k39D-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 6h20 -
(-) 		4 / 8 GLU A 125
ARG A 297
ARG A 128
ASP A 301
 None
 1.15A 3mjrD-6h20A:
undetectable		 3mjrD-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZU_A_X89A411_1
(FLAVOHEMOPROTEIN)		 6h20 -
(-) 		5 / 12 ILE A 130
LEU A  94
VAL A  96
LEU A 287
LEU A 151
 None
 1.24A 3ozuA-6h20A:
undetectable		 3ozuA-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 6h20 -
(-) 		4 / 7 ASP A 250
SER A 164
TYR A 276
ARG A 169
 ASN  A 401 (-2.9A)
ASN  A 401 (-2.9A)
ASN  A 401 ( 4.9A)
ASN  A 401 (-2.9A)
 0.99A 3pglA-6h20A:
undetectable		 3pglA-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 6h20 -
(-) 		4 / 7 ASP A 181
ALA A 182
ASP A 273
TYR A 276
 None
None
None
ASN  A 401 ( 4.9A)
 1.16A 3rodD-6h20A:
undetectable		 3rodD-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUK_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 6h20 -
(-) 		5 / 12 ILE A 298
LEU A 295
ALA A 127
VAL A  85
VAL A 291
 None
 1.05A 3rukA-6h20A:
undetectable		 3rukA-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 6h20 -
(-) 		4 / 8 GLN A 184
GLN A 274
LYS A 161
THR A 162
 None
ASN  A 401 ( 4.8A)
None
ASN  A 401 (-3.8A)
 1.20A 4d1yA-6h20A:
undetectable
4d1yB-6h20A:
undetectable		 4d1yA-6h20A:
undetectable
4d1yB-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 6h20 -
(-) 		5 / 12 SER A 102
THR A 212
THR A 211
ALA A 144
TYR A 276
 None
ASN  A 401 (-3.5A)
ASN  A 401 (-4.0A)
ASN  A 401 ( 4.3A)
ASN  A 401 ( 4.9A)
 1.13A 4dajB-6h20A:
0.2		 4dajB-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6h20 -
(-) 		5 / 11 ASP A 129
ARG A 297
VAL A 160
ILE A 158
ILE A  88
 None
 1.35A 4dz2A-6h20A:
undetectable
4dz2B-6h20A:
undetectable		 4dz2A-6h20A:
undetectable
4dz2B-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6h20 -
(-) 		5 / 11 ASP A 129
ARG A 297
VAL A 160
ILE A 158
ILE A  88
 None
 1.31A 4dz2A-6h20A:
undetectable
4dz2B-6h20A:
undetectable		 4dz2A-6h20A:
undetectable
4dz2B-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6h20 -
(-) 		5 / 10 ASP A 129
ARG A 297
VAL A 160
ILE A 158
ILE A  88
 None
 1.43A 4dz3A-6h20A:
undetectable		 4dz3A-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 6h20 -
(-) 		4 / 8 GLN A 184
ILE A 226
VAL A 205
PRO A 224
 None
 0.92A 4e1vA-6h20A:
undetectable		 4e1vA-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 6h20 -
(-) 		4 / 7 GLN A 184
ILE A 226
VAL A 205
PRO A 224
 None
 0.95A 4e1vB-6h20A:
undetectable		 4e1vB-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 6h20 -
(-) 		4 / 8 GLN A 184
ILE A 226
VAL A 205
PRO A 224
 None
 0.98A 4e1vG-6h20A:
undetectable		 4e1vG-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA603_1
(TRANSPORTER)		 6h20 -
(-) 		5 / 10 ASP A  99
TYR A 276
SER A 106
GLY A 117
ASP A 250
 None
ASN  A 401 ( 4.9A)
None
None
ASN  A 401 (-2.9A)
 1.42A 4mmcA-6h20A:
undetectable		 4mmcA-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 6h20 -
(-) 		5 / 12 ARG A 216
ILE A 194
ILE A 226
VAL A 197
ILE A 186
 None
 1.01A 4q1yB-6h20A:
undetectable		 4q1yB-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 6h20 -
(-) 		5 / 10 ASP A 129
ARG A 297
VAL A 160
ILE A 158
LEU A 287
 None
 1.36A 5hw8C-6h20A:
undetectable
5hw8H-6h20A:
undetectable		 5hw8C-6h20A:
undetectable
5hw8H-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 6h20 -
(-) 		3 / 3 THR A 177
SER A  71
TYR A 326
 None
 0.80A 5jsdA-6h20A:
undetectable		 5jsdA-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 6h20 -
(-) 		3 / 3 THR A 177
SER A  71
TYR A 326
 None
 0.81A 5jsdB-6h20A:
undetectable		 5jsdB-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 6h20 -
(-) 		3 / 3 THR A 177
SER A  71
TYR A 326
 None
 0.81A 5jsdC-6h20A:
undetectable		 5jsdC-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 6h20 -
(-) 		3 / 3 THR A 177
SER A  71
TYR A 326
 None
 0.80A 5jseA-6h20A:
undetectable		 5jseA-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 6h20 -
(-) 		3 / 3 THR A 177
SER A  71
TYR A 326
 None
 0.79A 5jseB-6h20A:
undetectable		 5jseB-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 6h20 -
(-) 		3 / 3 THR A 177
SER A  71
TYR A 326
 None
 0.80A 5jseC-6h20A:
undetectable		 5jseC-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 6h20 -
(-) 		4 / 6 PRO A 134
VAL A 137
VAL A  96
TYR A 139
 None
 0.94A 5pbeA-6h20A:
undetectable		 5pbeA-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 6h20 -
(-) 		5 / 12 PHE A 131
PHE A 290
ILE A 158
VAL A  96
VAL A  85
 None
 1.09A 6ap6A-6h20A:
undetectable		 6ap6A-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 6h20 -
(-) 		5 / 12 PHE A 131
PHE A 290
ILE A 158
VAL A  96
VAL A  85
 None
 1.10A 6ap6B-6h20A:
undetectable		 6ap6B-6h20A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_C_FK5C201_1
(PEPTIDYLPROLYL
ISOMERASE)		 6h20 -
(-) 		5 / 10 ASP A 129
ARG A 297
VAL A 160
ILE A 158
ILE A  88
 None
 1.48A 6mkeC-6h20A:
undetectable		 6mkeC-6h20A:
undetectable