SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6h7x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 6h7x -
(-) 		3 / 3 ALA A 278
VAL A 280
TRP A 283
 None
 0.86A 1nt5A-6h7xA:
undetectable		 1nt5A-6h7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 6h7x -
(-) 		3 / 3 ALA A 278
VAL A 280
TRP A 283
 None
 0.86A 1nt5B-6h7xA:
undetectable		 1nt5B-6h7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_D_CHDD702_0
(FERROCHELATASE)		 6h7x -
(-) 		3 / 3 ARG A  64
GLY A  95
PRO A  96
 None
 0.71A 2hreD-6h7xA:
undetectable		 2hreD-6h7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 6h7x -
(-) 		4 / 6 MET A 326
ARG A 353
PRO A 322
SER A 126
 None
 1.29A 2qd3B-6h7xA:
undetectable		 2qd3B-6h7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 6h7x -
(-) 		4 / 6 MET A 326
ILE A 346
PRO A 322
SER A 126
 None
 1.39A 2qd3B-6h7xA:
undetectable		 2qd3B-6h7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_B_C2FB314_1
(UNCHARACTERIZED
PROTEIN)		 6h7x -
(-) 		3 / 3 THR A 388
LYS A  43
GLU A 384
 None
 1.01A 3ijdB-6h7xA:
undetectable		 3ijdB-6h7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 6h7x -
(-) 		5 / 12 PHE A 100
ILE A 298
PHE A 311
ALA A 102
ILE A 108
 None
 1.36A 3ndiA-6h7xA:
undetectable		 3ndiA-6h7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6h7x -
(-) 		4 / 6 ILE A 103
GLY A 105
ILE A 346
LEU A 296
 None
 0.71A 4o8fB-6h7xA:
undetectable		 4o8fB-6h7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 6h7x -
(-) 		5 / 12 GLY A  89
VAL A 295
ILE A  75
ALA A  56
GLY A  57
 EDO  A1008 ( 4.2A)
None
None
None
None
 0.90A 5kb6A-6h7xA:
undetectable		 5kb6A-6h7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 6h7x -
(-) 		5 / 12 GLY A  89
VAL A 295
ILE A  75
ALA A  56
GLY A  57
 EDO  A1008 ( 4.2A)
None
None
None
None
 0.90A 5kb6B-6h7xA:
undetectable		 5kb6B-6h7xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 6h7x -
(-) 		5 / 10 ILE A 346
ALA A 122
LEU A 312
LEU A 304
LEU A 324
 None
 0.96A 6f6nA-6h7xA:
undetectable
6f6nB-6h7xA:
undetectable		 6f6nA-6h7xA:
undetectable
6f6nB-6h7xA:
undetectable