SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '9atc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 9atc ASPARTATE
TRANSCARBAMOYLASE
(Escherichia
coli) 		3 / 3 CYH B 109
CYH B 114
HIS B 117
 ZN  B   1 (-2.3A)
ZN  B   1 (-2.2A)
None
 0.69A 2iwkA-9atcB:
undetectable		 2iwkA-9atcB:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 9atc ASPARTATE
TRANSCARBAMOYLASE
(Escherichia
coli) 		3 / 3 CYH B 109
CYH B 114
HIS B 117
 ZN  B   1 (-2.3A)
ZN  B   1 (-2.2A)
None
 0.70A 2iwkB-9atcB:
undetectable		 2iwkB-9atcB:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 9atc ASPARTATE
TRANSCARBAMOYLASE
(Escherichia
coli) 		3 / 3 CYH B 109
CYH B 114
HIS B 117
 ZN  B   1 (-2.3A)
ZN  B   1 (-2.2A)
None
 0.78A 3dtuB-9atcB:
undetectable		 3dtuB-9atcB:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 9atc ASPARTATE
TRANSCARBAMOYLASE
(Escherichia
coli) 		3 / 3 CYH B 109
CYH B 114
HIS B 117
 ZN  B   1 (-2.3A)
ZN  B   1 (-2.2A)
None
 0.77A 3dtuD-9atcB:
undetectable		 3dtuD-9atcB:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 9atc ASPARTATE
TRANSCARBAMOYLASE
(Escherichia
coli) 		5 / 10 LEU B 136
SER B 124
ALA B  75
ILE B 134
PRO B 100
 None
 1.15A 4xj7C-9atcB:
undetectable
4xj7D-9atcB:
undetectable		 4xj7C-9atcB:
21.51
4xj7D-9atcB:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AIN_A_QMRA1207_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 9atc ASPARTATE
TRANSCARBAMOYLASE
(Escherichia
coli) 		5 / 10 VAL B 108
TYR B 140
CYH B 141
CYH B 138
VAL B 150
 None
None
ZN  B   1 (-2.2A)
ZN  B   1 (-2.3A)
None
 1.46A 5ainA-9atcB:
0.0
5ainB-9atcB:
0.0		 5ainA-9atcB:
21.40
5ainB-9atcB:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AIN_B_QMRB1207_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 9atc ASPARTATE
TRANSCARBAMOYLASE
(Escherichia
coli) 		5 / 10 VAL B 108
TYR B 140
CYH B 141
CYH B 138
VAL B 150
 None
None
ZN  B   1 (-2.2A)
ZN  B   1 (-2.3A)
None
 1.44A 5ainB-9atcB:
0.0
5ainC-9atcB:
0.0		 5ainB-9atcB:
21.40
5ainC-9atcB:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AIN_C_QMRC1207_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 9atc ASPARTATE
TRANSCARBAMOYLASE
(Escherichia
coli) 		5 / 10 VAL B 108
TYR B 140
CYH B 141
CYH B 138
VAL B 150
 None
None
ZN  B   1 (-2.2A)
ZN  B   1 (-2.3A)
None
 1.34A 5ainC-9atcB:
0.0
5ainD-9atcB:
undetectable		 5ainC-9atcB:
21.40
5ainD-9atcB:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AIN_D_QMRD1207_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 9atc ASPARTATE
TRANSCARBAMOYLASE
(Escherichia
coli) 		5 / 10 VAL B 108
TYR B 140
CYH B 141
CYH B 138
VAL B 150
 None
None
ZN  B   1 (-2.2A)
ZN  B   1 (-2.3A)
None
 1.44A 5ainD-9atcB:
0.0
5ainE-9atcB:
0.0		 5ainD-9atcB:
21.40
5ainE-9atcB:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AIN_E_QMRE1207_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 9atc ASPARTATE
TRANSCARBAMOYLASE
(Escherichia
coli) 		5 / 10 VAL B 150
VAL B 108
TYR B 140
CYH B 141
CYH B 138
 None
None
None
ZN  B   1 (-2.2A)
ZN  B   1 (-2.3A)
 1.40A 5ainA-9atcB:
0.0
5ainE-9atcB:
0.0		 5ainA-9atcB:
21.40
5ainE-9atcB:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 9atc ASPARTATE
TRANSCARBAMOYLASE
(Escherichia
coli) 		5 / 10 ILE B  21
ASN B 153
LEU B  74
LEU B  76
LEU B 151
 None
 1.23A 5y7pG-9atcB:
undetectable		 5y7pG-9atcB:
18.94