SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '9rub'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		5 / 12 LEU A 261
ILE A 272
GLY A 316
ALA A 317
SER A 318
 None
 1.07A 1cqeA-9rubA:
undetectable		 1cqeA-9rubA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		5 / 12 LEU A 261
ILE A 272
GLY A 316
ALA A 317
SER A 318
 None
 1.07A 1cqeB-9rubA:
undetectable		 1cqeB-9rubA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		4 / 8 TYR A  28
THR A 108
VAL A 307
VAL A 128
 None
 1.10A 1dz9A-9rubA:
undetectable		 1dz9A-9rubA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		4 / 4 ARG A 217
ALA A 218
ALA A 182
GLU A 178
 None
 1.14A 1e7bA-9rubA:
undetectable		 1e7bA-9rubA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		4 / 4 ARG A 217
ALA A 218
ALA A 182
GLU A 178
 None
 1.16A 1e7bB-9rubA:
undetectable		 1e7bB-9rubA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		4 / 5 ARG A 217
ALA A 218
ALA A 182
GLU A 178
 None
 1.08A 1e7cA-9rubA:
undetectable		 1e7cA-9rubA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N3Z_A_ADNA126_1
(RIBONUCLEASE,
SEMINAL)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		5 / 9 ALA A 177
LYS A 174
GLN A 219
ALA A 212
VAL A 211
 None
 1.47A 1n3zA-9rubA:
undetectable		 1n3zA-9rubA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_1
(POL POLYPROTEIN)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		5 / 10 LEU A 343
GLY A 316
ALA A 317
GLY A 264
THR A 322
 None
 1.02A 1t7iA-9rubA:
undetectable		 1t7iA-9rubA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IXL_A_PACA5000_0
(ARYLMALONATE
DECARBOXYLASE)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		5 / 10 PRO A  86
THR A  51
SER A  50
TYR A   7
GLY A  66
 None
 1.45A 3ixlA-9rubA:
1.6		 3ixlA-9rubA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI201_1
(PROTEIN S100-A4)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		5 / 9 PHE A 397
GLY A 398
PRO A 403
GLY A 370
ILE A 164
 None
None
None
None
FMT  A 601 ( 3.8A)
 1.15A 3ko0H-9rubA:
undetectable
3ko0I-9rubA:
undetectable		 3ko0H-9rubA:
13.22
3ko0I-9rubA:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		5 / 9 GLY A 394
PHE A 397
THR A 163
GLY A 162
ARG A 152
 None
 1.35A 4acaB-9rubA:
undetectable
4acaC-9rubA:
2.1		 4acaB-9rubA:
22.18
4acaC-9rubA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		3 / 3 LYS A 122
TYR A 120
ARG A 301
 None
 1.17A 4gc9A-9rubA:
undetectable		 4gc9A-9rubA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		3 / 3 LYS A  82
LEU A  80
ALA A  27
 None
 0.60A 4iizA-9rubA:
undetectable		 4iizA-9rubA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		4 / 7 ALA A 271
THR A 274
ALA A 275
THR A 233
 None
 1.02A 4qw0K-9rubA:
undetectable		 4qw0K-9rubA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		4 / 7 ALA A 271
THR A 274
ALA A 275
THR A 233
 None
 1.02A 4qw0Y-9rubA:
undetectable		 4qw0Y-9rubA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		4 / 7 GLU A  73
TYR A  72
ASP A 125
ALA A  27
 None
 1.15A 4zz8A-9rubA:
undetectable		 4zz8A-9rubA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		4 / 6 SER A 318
ARG A 278
GLY A 244
GLU A 245
 None
 1.04A 5btaA-9rubA:
undetectable
5btaB-9rubA:
undetectable
5btaC-9rubA:
undetectable		 5btaA-9rubA:
22.59
5btaB-9rubA:
20.29
5btaC-9rubA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		4 / 6 SER A 318
ARG A 278
GLY A 244
GLU A 245
 None
 1.10A 5btcA-9rubA:
undetectable
5btcC-9rubA:
undetectable
5btcD-9rubA:
undetectable		 5btcA-9rubA:
22.59
5btcC-9rubA:
22.59
5btcD-9rubA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		4 / 6 SER A 318
ARG A 278
GLY A 244
GLU A 245
 None
 1.07A 5btcA-9rubA:
undetectable
5btcB-9rubA:
undetectable
5btcC-9rubA:
undetectable		 5btcA-9rubA:
22.59
5btcB-9rubA:
20.29
5btcC-9rubA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		5 / 10 VAL A 262
ASP A 263
THR A 250
GLY A 197
LEU A 204
 None
 1.25A 5m5cE-9rubA:
undetectable		 5m5cE-9rubA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		4 / 7 TYR A  28
THR A 108
VAL A 307
VAL A 128
 None
 1.02A 5wk9A-9rubA:
undetectable		 5wk9A-9rubA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_1
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		5 / 12 LEU A 410
GLY A 406
ALA A 413
LEU A 390
ALA A 444
 None
 0.99A 5xv7A-9rubA:
undetectable		 5xv7A-9rubA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		5 / 12 ILE A 101
PHE A 136
GLN A 355
LEU A  25
PHE A 126
 None
 1.29A 5xxiA-9rubA:
undetectable		 5xxiA-9rubA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 9rub RIBULOSE-1,5-BISPHOS
PHATE CARBOXYLASE
(Rhodospirillum
rubrum) 		4 / 5 TYR A 246
ARG A 205
THR A 207
LEU A 210
 None
 1.32A 6nknW-9rubA:
undetectable		 6nknW-9rubA:
10.27